Divalproex sodium dosage forms and a process for their production

Divalproex sodium dosage forms and a process for their production

The present invention is directed to a new process for granulating valproate compounds, such as divalproex sodium, in which the compound is melted in the absence of a binder and admixed with one or more excipeints to produce granules. The resulting dosage forms have an increased drug loading factor...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Chermak, Todd, Qui, Yihong, Engh, Kevin, Faitsch, Lynn, Slade, Russell
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Chermak, Todd
Qui, Yihong
Engh, Kevin
Faitsch, Lynn
Slade, Russell
description The present invention is directed to a new process for granulating valproate compounds, such as divalproex sodium, in which the compound is melted in the absence of a binder and admixed with one or more excipeints to produce granules. The resulting dosage forms have an increased drug loading factor in the range of 75 w/w % to 90 w/w %.
format Patent
fullrecord <record><control><sourceid>uspatents_EFI</sourceid><recordid>TN_cdi_uspatents_applications_20020132010</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>20020132010</sourcerecordid><originalsourceid>FETCH-uspatents_applications_200201320103</originalsourceid><addsrcrecordid>eNrjZHB0ySxLzCkoyk-tUCjOT8kszVVIyS9OTE9VSMsvyi1WSMxLUUhUAMonpxYXg8QUSjJSM4tAIimlySWZ-Xk8DKxpiTnFqbxQmptB0801xNlDt7S4ILEkNa-kOD6xoCAnMzkRpLo43sjAwMjA0BiIDYxJUQsAzJE4tA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Divalproex sodium dosage forms and a process for their production</title><source>USPTO Published Applications</source><creator>Chermak, Todd ; Qui, Yihong ; Engh, Kevin ; Faitsch, Lynn ; Slade, Russell</creator><creatorcontrib>Chermak, Todd ; Qui, Yihong ; Engh, Kevin ; Faitsch, Lynn ; Slade, Russell</creatorcontrib><description>The present invention is directed to a new process for granulating valproate compounds, such as divalproex sodium, in which the compound is melted in the absence of a binder and admixed with one or more excipeints to produce granules. The resulting dosage forms have an increased drug loading factor in the range of 75 w/w % to 90 w/w %.</description><language>eng</language><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20020132010$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,873,885,64058</link.rule.ids><linktorsrc>$$Uhttps://patentcenter.uspto.gov/applications/09747912$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Chermak, Todd</creatorcontrib><creatorcontrib>Qui, Yihong</creatorcontrib><creatorcontrib>Engh, Kevin</creatorcontrib><creatorcontrib>Faitsch, Lynn</creatorcontrib><creatorcontrib>Slade, Russell</creatorcontrib><title>Divalproex sodium dosage forms and a process for their production</title><description>The present invention is directed to a new process for granulating valproate compounds, such as divalproex sodium, in which the compound is melted in the absence of a binder and admixed with one or more excipeints to produce granules. The resulting dosage forms have an increased drug loading factor in the range of 75 w/w % to 90 w/w %.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EFI</sourceid><recordid>eNrjZHB0ySxLzCkoyk-tUCjOT8kszVVIyS9OTE9VSMsvyi1WSMxLUUhUAMonpxYXg8QUSjJSM4tAIimlySWZ-Xk8DKxpiTnFqbxQmptB0801xNlDt7S4ILEkNa-kOD6xoCAnMzkRpLo43sjAwMjA0BiIDYxJUQsAzJE4tA</recordid><startdate>20020919</startdate><enddate>20020919</enddate><creator>Chermak, Todd</creator><creator>Qui, Yihong</creator><creator>Engh, Kevin</creator><creator>Faitsch, Lynn</creator><creator>Slade, Russell</creator><scope>EFI</scope></search><sort><creationdate>20020919</creationdate><title>Divalproex sodium dosage forms and a process for their production</title><author>Chermak, Todd ; Qui, Yihong ; Engh, Kevin ; Faitsch, Lynn ; Slade, Russell</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_applications_200201320103</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2002</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Chermak, Todd</creatorcontrib><creatorcontrib>Qui, Yihong</creatorcontrib><creatorcontrib>Engh, Kevin</creatorcontrib><creatorcontrib>Faitsch, Lynn</creatorcontrib><creatorcontrib>Slade, Russell</creatorcontrib><collection>USPTO Published Applications</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Chermak, Todd</au><au>Qui, Yihong</au><au>Engh, Kevin</au><au>Faitsch, Lynn</au><au>Slade, Russell</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Divalproex sodium dosage forms and a process for their production</title><date>2002-09-19</date><risdate>2002</risdate><abstract>The present invention is directed to a new process for granulating valproate compounds, such as divalproex sodium, in which the compound is melted in the absence of a binder and admixed with one or more excipeints to produce granules. The resulting dosage forms have an increased drug loading factor in the range of 75 w/w % to 90 w/w %.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_uspatents_applications_20020132010
source USPTO Published Applications
title Divalproex sodium dosage forms and a process for their production
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T13%3A36%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-uspatents_EFI&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Chermak,%20Todd&rft.date=2002-09-19&rft_id=info:doi/&rft_dat=%3Cuspatents_EFI%3E20020132010%3C/uspatents_EFI%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true