Method for identifying or screening agonist and antagonist to PPAR

A method for identifying or screening an agonist for or antagonist to a peroxisome proliferator activated receptor (PPAR) which comprises allowing a test cell and a substance to be tested to coexist, and detecting a change in a ligand-dependent interaction between the PPAR and a coactivator in the t...

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Hauptverfasser:	Taniguchi, Tomoyasu, Mizukami, Junko
Format:	Patent
Sprache:	eng
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creator	Taniguchi, Tomoyasu Mizukami, Junko
description	A method for identifying or screening an agonist for or antagonist to a peroxisome proliferator activated receptor (PPAR) which comprises allowing a test cell and a substance to be tested to coexist, and detecting a change in a ligand-dependent interaction between the PPAR and a coactivator in the test cells due to the substance to be tested by measuring the expression of a reporter gene as an index.
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title	Method for identifying or screening agonist and antagonist to PPAR
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