FIBER OPTIC BIOSENSOR FOR SELECTIVELY DETECTING OLIGONUCLEOTIDE SPECIES IN A MIXED FLUID SAMPLE

The present invention provides biosensors, apparatus and methods for selectively detecting at least one complementary oligonucleotide target specie in a fluid sample containing a mixture of different oligonucleotide fragments. One preferred embodiment of the biosensor is as a unitary fiber optic array having species of single stranded nucleic acid disposed as individual deposits in aligned organization upon multiple strand end faces at differing spatial positions on the distal array end surface.