PROCESS FOR DETECTING A KNOWN SEQUENCE IN GENOMIC DNA
Described is a process for screening genomic DNA samples for inherited conditions comprising selectively amplifying a portion of the genomic DNA using a primer that is substantially complementary to the portion but may have at least one mismatch nucleotide at or near one end. If the portion is ampli...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | Described is a process for screening genomic DNA samples for inherited conditions comprising selectively amplifying a portion of the genomic DNA using a primer that is substantially complementary to the portion but may have at least one mismatch nucleotide at or near one end. If the portion is amplified, hybridizing a probe to it, then, attaching the hybridized probe complex to a solid support and detecting the complex, if any. |
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