OLIGONUCLEOTIDES FOR CONTROLLING TAU SPLICING, AND USES THEREOF

The present invention provides a tau exon 10 skipping-promoting antisense oligonucleotide containing at least one 2′-O, 4′-C-ethylene-bridged nucleic acid, and a nucleotide sequence complementary to a sequence consisting of at least 10 continuous nucleotides in a region consisting of the nucleotide...

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Hauptverfasser: KNC LABORATORIES CO., LTD, NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM
Format: Patent
Sprache:eng
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