Methods and Compositions for Upregulation of GATA Activity
A novel method of identifying compounds capable of upregulating GATA activity is disclosed. The method includes providing a sample of cells that express GATA, providing a sample of a candidate compound, contacting the cell sample and the compound sample, and measuring a quantitative indicator of GAT...
Gespeichert in:
1. Verfasser: | |
---|---|
Format: | Patent |
Sprache: | eng |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | REDDY US THERAPEUTICS, INC |
description | A novel method of identifying compounds capable of upregulating GATA activity is disclosed. The method includes providing a sample of cells that express GATA, providing a sample of a candidate compound, contacting the cell sample and the compound sample, and measuring a quantitative indicator of GATA activity within the cell sample after the contacting step. GATA inducers identified by the method and uses therefore to upregulate GATA activity in subjects and to prevent or treat atherosclerosis or diabetes in subjects are also described. |
format | Patent |
fullrecord | <record><control><sourceid>uspatents_EFI</sourceid><recordid>TN_cdi_uspatents_applications_12113426</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>20080275049</sourcerecordid><originalsourceid>FETCH-uspatents_applications_121134263</originalsourceid><addsrcrecordid>eNrjZLDyTS3JyE8pVkjMS1Fwzs8tyC_OLMnMzytWSMsvUggtKEpNL81JBIko5KcpuDuGOCo4JpdklmWWVPIwsKYl5hSn8kJpbgY1N9cQZw_d0uKCxJLUvJLi-MSCgpzMZLD24nhDI0NDYxMjM2OiFQIAoPQ0Zg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Methods and Compositions for Upregulation of GATA Activity</title><source>USPTO Published Applications</source><creator>REDDY US THERAPEUTICS, INC</creator><creatorcontrib>REDDY US THERAPEUTICS, INC</creatorcontrib><description>A novel method of identifying compounds capable of upregulating GATA activity is disclosed. The method includes providing a sample of cells that express GATA, providing a sample of a candidate compound, contacting the cell sample and the compound sample, and measuring a quantitative indicator of GATA activity within the cell sample after the contacting step. GATA inducers identified by the method and uses therefore to upregulate GATA activity in subjects and to prevent or treat atherosclerosis or diabetes in subjects are also described.</description><language>eng</language><creationdate>2008</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20080275049$$EPDF$$P50$$Guspatents$$Hfree_for_read</linktopdf><link.rule.ids>230,308,780,873,885,64048</link.rule.ids><linktorsrc>$$Uhttps://patentcenter.uspto.gov/applications/12113426$$EView_record_in_USPTO$$FView_record_in_$$GUSPTO$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>REDDY US THERAPEUTICS, INC</creatorcontrib><title>Methods and Compositions for Upregulation of GATA Activity</title><description>A novel method of identifying compounds capable of upregulating GATA activity is disclosed. The method includes providing a sample of cells that express GATA, providing a sample of a candidate compound, contacting the cell sample and the compound sample, and measuring a quantitative indicator of GATA activity within the cell sample after the contacting step. GATA inducers identified by the method and uses therefore to upregulate GATA activity in subjects and to prevent or treat atherosclerosis or diabetes in subjects are also described.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2008</creationdate><recordtype>patent</recordtype><sourceid>EFI</sourceid><recordid>eNrjZLDyTS3JyE8pVkjMS1Fwzs8tyC_OLMnMzytWSMsvUggtKEpNL81JBIko5KcpuDuGOCo4JpdklmWWVPIwsKYl5hSn8kJpbgY1N9cQZw_d0uKCxJLUvJLi-MSCgpzMZLD24nhDI0NDYxMjM2OiFQIAoPQ0Zg</recordid><startdate>20080501</startdate><enddate>20080501</enddate><creator>REDDY US THERAPEUTICS, INC</creator><scope>EFI</scope></search><sort><creationdate>20080501</creationdate><title>Methods and Compositions for Upregulation of GATA Activity</title></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-uspatents_applications_121134263</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2008</creationdate><toplevel>online_resources</toplevel><creatorcontrib>REDDY US THERAPEUTICS, INC</creatorcontrib><collection>USPTO Published Applications</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><aucorp>REDDY US THERAPEUTICS, INC</aucorp><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Methods and Compositions for Upregulation of GATA Activity</title><date>2008-05-01</date><risdate>2008</risdate><abstract>A novel method of identifying compounds capable of upregulating GATA activity is disclosed. The method includes providing a sample of cells that express GATA, providing a sample of a candidate compound, contacting the cell sample and the compound sample, and measuring a quantitative indicator of GATA activity within the cell sample after the contacting step. GATA inducers identified by the method and uses therefore to upregulate GATA activity in subjects and to prevent or treat atherosclerosis or diabetes in subjects are also described.</abstract><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | eng |
recordid | cdi_uspatents_applications_12113426 |
source | USPTO Published Applications |
title | Methods and Compositions for Upregulation of GATA Activity |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T01%3A37%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-uspatents_EFI&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.aucorp=REDDY%20US%20THERAPEUTICS,%20INC&rft.date=2008-05-01&rft_id=info:doi/&rft_dat=%3Cuspatents_EFI%3E20080275049%3C/uspatents_EFI%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |