Design of a low-cost equipment for optical hyperthermia

[EN] A laser equipment is presented which has been specifically designed for optical hyperthermia. Such specificity in the design has allowed implementation at costs significantly lower than other options currently available in the market. The developed equipment includes a 808 nm laser whose output...

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Hauptverfasser: Montes-Robles, Roberto, Hernández-Montoto, Andy, Ibáñez Civera, Francisco Javier, Masot Peris, Rafael, De La Torre-Paredes, Cristina, Martínez-Máñez, Ramón, Garcia-Breijo, Eduardo, Fraile Muñoz, Rubén
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Zusammenfassung:[EN] A laser equipment is presented which has been specifically designed for optical hyperthermia. Such specificity in the design has allowed implementation at costs significantly lower than other options currently available in the market. The developed equipment includes a 808 nm laser whose output power is up to 500 mW. It also incorporates additional devices that help the user in calibrating the system and supervising it while functioning. The performance of a prototype is tested by running two hyperthermia experiments: one involving gold nanorods, and the other using gold nanostars. The specific set-up of this prototype has allowed laser irradiation with radiated power densities up to 4W/cm(2). (C) 2016 Elsevier B.V. All rights reserved. This work has been carried out in the context of project "Development of electronic devices and equipment for detection and actuation based on new electronic technologies. Applications in the field of biomedicine" (grant number: MAT2015-64139-C4-3-R) and in coordination with project number MAT2015-64139-C4-1-R, both of them financed by the Spanish Ministry for Economy and Competitiveness in the framework of the Plan Estatal de Investigacion Cientifica y Tecnica y de Innovacion 2013-2016. Financial support from the Generalitat Valenciana (PROMETEOII/2014/047) and from the UPV (Erasmus Mundus EuroInkaNet project, 2013 call) are gratefully acknowledged too. Montes-Robles, R.; Hernández-Montoto, A.; Ibáñez Civera, FJ.; Masot Peris, R.; De La Torre-Paredes, C.; Martínez-Máñez, R.; Garcia-Breijo, E... (2017). Design of a low-cost equipment for optical hyperthermia. Sensors and Actuators A Physical. 255:61-70. https://doi.org/10.1016/j.sna.2016.12.018