Coronary atherosclerosis distribution and the effect of blood glucose level on operative mortality/morbidity in diabetic patients undergoing coronary artery bypass grafting surgery: a single center experience
The study aim was to investigate the effect of blood glucose level on atherosclerotic lesion distribution and the contribution to the operative mortality/morbidity in diabetic patients who underwent coronary artery bypass grafting (CABG). Between 1986-2003, a total of 2095 patients with diabetes mel...
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| Veröffentlicht in: | Anadolu kardiyoloji dergisi : AKD 2007-06, Vol.7 (2), p.158-163 |
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| container_title | Anadolu kardiyoloji dergisi : AKD |
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| creator | Tütün, Ufuk Ciçekçioğlu, Ferit Budak, Baran Temürtürkan, Mehtap Parlar, A Ihsan Seren, Mustafa Ulus, A Tulga Katircioğlu, S Fehmi |
| description | The study aim was to investigate the effect of blood glucose level on atherosclerotic lesion distribution and the contribution to the operative mortality/morbidity in diabetic patients who underwent coronary artery bypass grafting (CABG).
Between 1986-2003, a total of 2095 patients with diabetes mellitus underwent CABG. The analysis was carried out retrospectively from the clinical records. The patients were divided into four groups according to the blood glucose levels that were obtained when they first applied to hospital; Group 1 (492 patients with blood glucose < 120 mg/dl), group 2 (1112 patients with blood glucose - 120-200 mg/dl, group 3 (261 patients with blood glucose 201-250 mg/dl) and group 4 (230 patients with blood glucose > 250 mg/dl). One way ANOVA test was used for the statistical analysis of continuous variables and Chi-square test was used for analyzing the categorical variables.
Emergent operation rate due to acute ischemia gradually increased from Group 1 to Group 4 and reached 6.6% in Group 4 (p=0.005). Operation time and the duration of cardiopulmonary bypass and cross clamp were significantly longer in patients with high blood glucose levels (p |
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Between 1986-2003, a total of 2095 patients with diabetes mellitus underwent CABG. The analysis was carried out retrospectively from the clinical records. The patients were divided into four groups according to the blood glucose levels that were obtained when they first applied to hospital; Group 1 (492 patients with blood glucose < 120 mg/dl), group 2 (1112 patients with blood glucose - 120-200 mg/dl, group 3 (261 patients with blood glucose 201-250 mg/dl) and group 4 (230 patients with blood glucose > 250 mg/dl). One way ANOVA test was used for the statistical analysis of continuous variables and Chi-square test was used for analyzing the categorical variables.
Emergent operation rate due to acute ischemia gradually increased from Group 1 to Group 4 and reached 6.6% in Group 4 (p=0.005). Operation time and the duration of cardiopulmonary bypass and cross clamp were significantly longer in patients with high blood glucose levels (p<0.05). Necessity for inotropic drug administration postoperatively (p<0.05) and mechanical support (p<0.05) were significantly higher also. The hospital mortality in group 3 was 9.6% and in group 4 was 11.3% (p=0.09). No statistically significant difference was found in terms of morbidity between the groups (p>0.05). The multi-vessel coronary artery disease was more common in groups with high blood glucose level (p<0.05). As the blood glucose level raised, patients were more frequently (p<0.05) confronted with distal left anterior descending artery, middle circumflex artery and right coronary artery lesions.
Uncontrolled blood glucose level not only increased the perioperative complications but also the incidence of middle and distal coronary artery lesions. It is necessary to diagnose and aggressively treat the high blood glucose level especially before the CABG.]]></description><identifier>ISSN: 1302-8723</identifier><identifier>EISSN: 1308-0032</identifier><identifier>PMID: 17513212</identifier><language>eng</language><publisher>Turkey: Aves Yayıncılık</publisher><subject>Blood Glucose ; Cardiovascular diseases ; Cerrahi prosedürler, operatif ; Coronary Artery Bypass ; Coronary Artery Disease ; Coronary Artery Disease - blood ; Coronary Artery Disease - epidemiology ; Coronary Artery Disease - mortality ; Coronary Artery Disease - pathology ; Coronary Artery Disease - surgery ; Diabetes Mellitus ; Female ; Geriyedönük çalışma ; Hastalık şiddeti belirtileri ; Humans ; İntraoperatif komplikasyonlar ; Intraoperative Complications ; Kan şekeri ; Kardiyovasküler hastalıklar ; Koroner arter hastalığı ; Koroner arter köprüleme ; Male ; Medical Records ; Middle Aged ; Postoperative Complications ; Retrospective Studies ; Risk Factors ; Severity of Illness Index ; Surgical procedures, operative ; Tedavi sonucu ; Treatment Outcome ; Turkey - epidemiology</subject><ispartof>Anadolu kardiyoloji dergisi : AKD, 2007-06, Vol.7 (2), p.158-163</ispartof><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,778,782,883</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17513212$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tütün, Ufuk</creatorcontrib><creatorcontrib>Ciçekçioğlu, Ferit</creatorcontrib><creatorcontrib>Budak, Baran</creatorcontrib><creatorcontrib>Temürtürkan, Mehtap</creatorcontrib><creatorcontrib>Parlar, A Ihsan</creatorcontrib><creatorcontrib>Seren, Mustafa</creatorcontrib><creatorcontrib>Ulus, A Tulga</creatorcontrib><creatorcontrib>Katircioğlu, S Fehmi</creatorcontrib><title>Coronary atherosclerosis distribution and the effect of blood glucose level on operative mortality/morbidity in diabetic patients undergoing coronary artery bypass grafting surgery: a single center experience</title><title>Anadolu kardiyoloji dergisi : AKD</title><addtitle>Anadolu Kardiyol Derg</addtitle><description><![CDATA[The study aim was to investigate the effect of blood glucose level on atherosclerotic lesion distribution and the contribution to the operative mortality/morbidity in diabetic patients who underwent coronary artery bypass grafting (CABG).
Between 1986-2003, a total of 2095 patients with diabetes mellitus underwent CABG. The analysis was carried out retrospectively from the clinical records. The patients were divided into four groups according to the blood glucose levels that were obtained when they first applied to hospital; Group 1 (492 patients with blood glucose < 120 mg/dl), group 2 (1112 patients with blood glucose - 120-200 mg/dl, group 3 (261 patients with blood glucose 201-250 mg/dl) and group 4 (230 patients with blood glucose > 250 mg/dl). One way ANOVA test was used for the statistical analysis of continuous variables and Chi-square test was used for analyzing the categorical variables.
Emergent operation rate due to acute ischemia gradually increased from Group 1 to Group 4 and reached 6.6% in Group 4 (p=0.005). Operation time and the duration of cardiopulmonary bypass and cross clamp were significantly longer in patients with high blood glucose levels (p<0.05). Necessity for inotropic drug administration postoperatively (p<0.05) and mechanical support (p<0.05) were significantly higher also. The hospital mortality in group 3 was 9.6% and in group 4 was 11.3% (p=0.09). No statistically significant difference was found in terms of morbidity between the groups (p>0.05). The multi-vessel coronary artery disease was more common in groups with high blood glucose level (p<0.05). As the blood glucose level raised, patients were more frequently (p<0.05) confronted with distal left anterior descending artery, middle circumflex artery and right coronary artery lesions.
Uncontrolled blood glucose level not only increased the perioperative complications but also the incidence of middle and distal coronary artery lesions. It is necessary to diagnose and aggressively treat the high blood glucose level especially before the CABG.]]></description><subject>Blood Glucose</subject><subject>Cardiovascular diseases</subject><subject>Cerrahi prosedürler, operatif</subject><subject>Coronary Artery Bypass</subject><subject>Coronary Artery Disease</subject><subject>Coronary Artery Disease - blood</subject><subject>Coronary Artery Disease - epidemiology</subject><subject>Coronary Artery Disease - mortality</subject><subject>Coronary Artery Disease - pathology</subject><subject>Coronary Artery Disease - surgery</subject><subject>Diabetes Mellitus</subject><subject>Female</subject><subject>Geriyedönük çalışma</subject><subject>Hastalık şiddeti belirtileri</subject><subject>Humans</subject><subject>İntraoperatif komplikasyonlar</subject><subject>Intraoperative Complications</subject><subject>Kan şekeri</subject><subject>Kardiyovasküler hastalıklar</subject><subject>Koroner arter hastalığı</subject><subject>Koroner arter köprüleme</subject><subject>Male</subject><subject>Medical Records</subject><subject>Middle Aged</subject><subject>Postoperative Complications</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Severity of Illness Index</subject><subject>Surgical procedures, operative</subject><subject>Tedavi sonucu</subject><subject>Treatment Outcome</subject><subject>Turkey - epidemiology</subject><issn>1302-8723</issn><issn>1308-0032</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kU1O5DAQhSMEohngBgjVil00jp203exQi4GRkNjAuuWfcjA4cbAdRN-SI42hGTZVz_WevirJe9VRw4ioCWF0_0vTWnDKFtWvlJ4J6fiSt4fVouFdw2hDj6qPdYhhlHELMj9hDEn7z-oSGJdydGrOLowgRwPFB7QWdYZgQfkQDPR-1iEheHxDDyUYJowyuzeEIcQsvcvb30UpZ4oCNxasVJidhqnEcMwJ5tFg7IMbe9A_x8SMpantJFOCPkqbP_00x77ML0FCKm-PoAsCI-B72VtwGk-qAyt9wtPvflw9_rl-WN_Wd_c3f9dXd_VEGcm14tQ0LRUGO9NIKzm2FJGTVi1XwrZy1ZKO4lJra0QnOs5EZ7nhEm2rV41i7Lg623FnL1-UGzZTdEM5fcO5YMtiX-zsKYbXGVPeDC5p9F6OGOa04aRrVlyQEjz_Ds5qQPOD-f9F7B8HxJWN</recordid><startdate>20070601</startdate><enddate>20070601</enddate><creator>Tütün, Ufuk</creator><creator>Ciçekçioğlu, Ferit</creator><creator>Budak, Baran</creator><creator>Temürtürkan, Mehtap</creator><creator>Parlar, A Ihsan</creator><creator>Seren, Mustafa</creator><creator>Ulus, A Tulga</creator><creator>Katircioğlu, S Fehmi</creator><general>Aves Yayıncılık</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>GIY</scope><scope>GIZ</scope><scope>GJA</scope><scope>GJB</scope></search><sort><creationdate>20070601</creationdate><title>Coronary atherosclerosis distribution and the effect of blood glucose level on operative mortality/morbidity in diabetic patients undergoing coronary artery bypass grafting surgery: a single center experience</title><author>Tütün, Ufuk ; Ciçekçioğlu, Ferit ; Budak, Baran ; Temürtürkan, Mehtap ; Parlar, A Ihsan ; Seren, Mustafa ; Ulus, A Tulga ; Katircioğlu, S Fehmi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p230t-b72d1428de5d1afa7e42ee704b698f4a94052e6ccfd85857385f7d7aef4c91b33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Blood Glucose</topic><topic>Cardiovascular diseases</topic><topic>Cerrahi prosedürler, operatif</topic><topic>Coronary Artery Bypass</topic><topic>Coronary Artery Disease</topic><topic>Coronary Artery Disease - blood</topic><topic>Coronary Artery Disease - epidemiology</topic><topic>Coronary Artery Disease - mortality</topic><topic>Coronary Artery Disease - pathology</topic><topic>Coronary Artery Disease - surgery</topic><topic>Diabetes Mellitus</topic><topic>Female</topic><topic>Geriyedönük çalışma</topic><topic>Hastalık şiddeti belirtileri</topic><topic>Humans</topic><topic>İntraoperatif komplikasyonlar</topic><topic>Intraoperative Complications</topic><topic>Kan şekeri</topic><topic>Kardiyovasküler hastalıklar</topic><topic>Koroner arter hastalığı</topic><topic>Koroner arter köprüleme</topic><topic>Male</topic><topic>Medical Records</topic><topic>Middle Aged</topic><topic>Postoperative Complications</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Severity of Illness Index</topic><topic>Surgical procedures, operative</topic><topic>Tedavi sonucu</topic><topic>Treatment Outcome</topic><topic>Turkey - epidemiology</topic><toplevel>online_resources</toplevel><creatorcontrib>Tütün, Ufuk</creatorcontrib><creatorcontrib>Ciçekçioğlu, Ferit</creatorcontrib><creatorcontrib>Budak, Baran</creatorcontrib><creatorcontrib>Temürtürkan, Mehtap</creatorcontrib><creatorcontrib>Parlar, A Ihsan</creatorcontrib><creatorcontrib>Seren, Mustafa</creatorcontrib><creatorcontrib>Ulus, A Tulga</creatorcontrib><creatorcontrib>Katircioğlu, S Fehmi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>ULAKBIM - Mühendislik ve Temel Bilimler Veri Tabani</collection><collection>ULAKBIM - Yaşam Bilimleri Veri Tabani</collection><collection>ULAKBIM - Turk Sosyal Bilimler Veri Tabani</collection><collection>ULAKBIM - Türk Tıp Veri Tabani</collection><jtitle>Anadolu kardiyoloji dergisi : AKD</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tütün, Ufuk</au><au>Ciçekçioğlu, Ferit</au><au>Budak, Baran</au><au>Temürtürkan, Mehtap</au><au>Parlar, A Ihsan</au><au>Seren, Mustafa</au><au>Ulus, A Tulga</au><au>Katircioğlu, S Fehmi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Coronary atherosclerosis distribution and the effect of blood glucose level on operative mortality/morbidity in diabetic patients undergoing coronary artery bypass grafting surgery: a single center experience</atitle><jtitle>Anadolu kardiyoloji dergisi : AKD</jtitle><addtitle>Anadolu Kardiyol Derg</addtitle><date>2007-06-01</date><risdate>2007</risdate><volume>7</volume><issue>2</issue><spage>158</spage><epage>163</epage><pages>158-163</pages><issn>1302-8723</issn><eissn>1308-0032</eissn><abstract><![CDATA[The study aim was to investigate the effect of blood glucose level on atherosclerotic lesion distribution and the contribution to the operative mortality/morbidity in diabetic patients who underwent coronary artery bypass grafting (CABG).
Between 1986-2003, a total of 2095 patients with diabetes mellitus underwent CABG. The analysis was carried out retrospectively from the clinical records. The patients were divided into four groups according to the blood glucose levels that were obtained when they first applied to hospital; Group 1 (492 patients with blood glucose < 120 mg/dl), group 2 (1112 patients with blood glucose - 120-200 mg/dl, group 3 (261 patients with blood glucose 201-250 mg/dl) and group 4 (230 patients with blood glucose > 250 mg/dl). One way ANOVA test was used for the statistical analysis of continuous variables and Chi-square test was used for analyzing the categorical variables.
Emergent operation rate due to acute ischemia gradually increased from Group 1 to Group 4 and reached 6.6% in Group 4 (p=0.005). Operation time and the duration of cardiopulmonary bypass and cross clamp were significantly longer in patients with high blood glucose levels (p<0.05). Necessity for inotropic drug administration postoperatively (p<0.05) and mechanical support (p<0.05) were significantly higher also. The hospital mortality in group 3 was 9.6% and in group 4 was 11.3% (p=0.09). No statistically significant difference was found in terms of morbidity between the groups (p>0.05). The multi-vessel coronary artery disease was more common in groups with high blood glucose level (p<0.05). As the blood glucose level raised, patients were more frequently (p<0.05) confronted with distal left anterior descending artery, middle circumflex artery and right coronary artery lesions.
Uncontrolled blood glucose level not only increased the perioperative complications but also the incidence of middle and distal coronary artery lesions. It is necessary to diagnose and aggressively treat the high blood glucose level especially before the CABG.]]></abstract><cop>Turkey</cop><pub>Aves Yayıncılık</pub><pmid>17513212</pmid><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Blood Glucose Cardiovascular diseases Cerrahi prosedürler, operatif Coronary Artery Bypass Coronary Artery Disease Coronary Artery Disease - blood Coronary Artery Disease - epidemiology Coronary Artery Disease - mortality Coronary Artery Disease - pathology Coronary Artery Disease - surgery Diabetes Mellitus Female Geriyedönük çalışma Hastalık şiddeti belirtileri Humans İntraoperatif komplikasyonlar Intraoperative Complications Kan şekeri Kardiyovasküler hastalıklar Koroner arter hastalığı Koroner arter köprüleme Male Medical Records Middle Aged Postoperative Complications Retrospective Studies Risk Factors Severity of Illness Index Surgical procedures, operative Tedavi sonucu Treatment Outcome Turkey - epidemiology |
| title | Coronary atherosclerosis distribution and the effect of blood glucose level on operative mortality/morbidity in diabetic patients undergoing coronary artery bypass grafting surgery: a single center experience |
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