In vitro testing for genotoxicity of 4-CPA by sister chromatid exchange in human lymphocyte culture
Certain phenoxyacetate derivatives used as plant growth regulators act as plant hormones. 2,4-D dichlorophenoxyacetic acid and 4-chlorophenoxyacetic acid are widely used in vegetable growing, especially tomatoes, in our region. These phenoxyacetic acid compounds are a potential hazard for the enviro...
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Veröffentlicht in: | Turkish journal of medical sciences 2005, Vol.35 (2), p.75-78 |
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creator | AÇIKBAŞ, İbrahim BAĞCI, Gülseren DEMİR, Göksemin BAĞCI, Hüseyin |
description | Certain phenoxyacetate derivatives used as plant growth regulators act as plant hormones. 2,4-D dichlorophenoxyacetic acid and 4-chlorophenoxyacetic acid are widely used in vegetable growing, especially tomatoes, in our region. These phenoxyacetic acid compounds are a potential hazard for the environment. There are conflicting results and inconsistent data about these herbicides in the literature. This is the first report of genotoxicity of 4-CPA evaluated by sister chromatid exchange in human lymphocyte culture. No significant change was found in sister chromatid exchange frequency at the tested 4-CPA concentration. |
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subjects | Anketler Araştırma teknikleri Genetic processes Genetik oluşumlar In vitro Investigative techniques Kardeş kromatid değişimi Lenfosit kültür testi, karma Lymphocyte Culture Test, Mixed Mutagenicity Tests Mutajenite testleri Questionnaires Sister Chromatid Exchange |
title | In vitro testing for genotoxicity of 4-CPA by sister chromatid exchange in human lymphocyte culture |
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