In vitro testing for genotoxicity of 4-CPA by sister chromatid exchange in human lymphocyte culture

Certain phenoxyacetate derivatives used as plant growth regulators act as plant hormones. 2,4-D dichlorophenoxyacetic acid and 4-chlorophenoxyacetic acid are widely used in vegetable growing, especially tomatoes, in our region. These phenoxyacetic acid compounds are a potential hazard for the enviro...

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Veröffentlicht in:Turkish journal of medical sciences 2005, Vol.35 (2), p.75-78
Hauptverfasser: AÇIKBAŞ, İbrahim, BAĞCI, Gülseren, DEMİR, Göksemin, BAĞCI, Hüseyin
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container_start_page 75
container_title Turkish journal of medical sciences
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creator AÇIKBAŞ, İbrahim
BAĞCI, Gülseren
DEMİR, Göksemin
BAĞCI, Hüseyin
description Certain phenoxyacetate derivatives used as plant growth regulators act as plant hormones. 2,4-D dichlorophenoxyacetic acid and 4-chlorophenoxyacetic acid are widely used in vegetable growing, especially tomatoes, in our region. These phenoxyacetic acid compounds are a potential hazard for the environment. There are conflicting results and inconsistent data about these herbicides in the literature. This is the first report of genotoxicity of 4-CPA evaluated by sister chromatid exchange in human lymphocyte culture. No significant change was found in sister chromatid exchange frequency at the tested 4-CPA concentration.
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source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; TÜBİTAK Scientific Journals
subjects Anketler
Araştırma teknikleri
Genetic processes
Genetik oluşumlar
In vitro
Investigative techniques
Kardeş kromatid değişimi
Lenfosit kültür testi, karma
Lymphocyte Culture Test, Mixed
Mutagenicity Tests
Mutajenite testleri
Questionnaires
Sister Chromatid Exchange
title In vitro testing for genotoxicity of 4-CPA by sister chromatid exchange in human lymphocyte culture
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