Epstein-Barr Virus Latent Membrane Protein 1 (LMP-1) in Hodgkin's Lymphoma Patients in Turkey
Epstein-Barr virus (EBV) has been implicated as a contributing factor in the development of Hodgkin's lymphoma. The aim of this study was to elucidate the association of Hodgkin's lymphoma with EBV in a Turkish population using immunohistochemical detection of LMP-1. We studied a total of...
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| Veröffentlicht in: | Turkish journal of haematology 2001-06, Vol.18 (2), p.123-126 |
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| container_title | Turkish journal of haematology |
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| creator | Ataoğlu, Ö Fen, T Süer, Ö Dağlı, M Akı, Z Yamaç, K |
| description | Epstein-Barr virus (EBV) has been implicated as a contributing factor in the development of Hodgkin's lymphoma. The aim of this study was to elucidate the association of Hodgkin's lymphoma with EBV in a Turkish population using immunohistochemical detection of LMP-1. We studied a total of 21 consecutive cases of Hodgkin's lymphoma from Turkey. LMP-1 protein was detected in 9 of 21 (42.8%) cases. LMP-1 was positive in 4 of 7 (57%) mixed cellularity and 5 of 13 (38.4%) nodular sclerosis subtype. The results of the current study suggests a strong association of Epstein-Barr virus with Hodgkin's lymphoma in Turkey and, together with those reported previously showed that Epstein-Barr virus correlated with mixed cellular type, with a slight male predominancy while there was no correlation with age. |
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The aim of this study was to elucidate the association of Hodgkin's lymphoma with EBV in a Turkish population using immunohistochemical detection of LMP-1. We studied a total of 21 consecutive cases of Hodgkin's lymphoma from Turkey. LMP-1 protein was detected in 9 of 21 (42.8%) cases. LMP-1 was positive in 4 of 7 (57%) mixed cellularity and 5 of 13 (38.4%) nodular sclerosis subtype. 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The aim of this study was to elucidate the association of Hodgkin's lymphoma with EBV in a Turkish population using immunohistochemical detection of LMP-1. We studied a total of 21 consecutive cases of Hodgkin's lymphoma from Turkey. LMP-1 protein was detected in 9 of 21 (42.8%) cases. LMP-1 was positive in 4 of 7 (57%) mixed cellularity and 5 of 13 (38.4%) nodular sclerosis subtype. The results of the current study suggests a strong association of Epstein-Barr virus with Hodgkin's lymphoma in Turkey and, together with those reported previously showed that Epstein-Barr virus correlated with mixed cellular type, with a slight male predominancy while there was no correlation with age.</description><subject>Epstein-Barr Virus Infections</subject><subject>Epstein-barr virüs enfeksiyonları</subject><subject>Herpesvirus 4, Human</subject><subject>Herpesvirüs 4, insan</subject><subject>Lenfom</subject><subject>Lymphoma</subject><subject>Neoplasms</subject><subject>Neoplazmlar</subject><subject>Turkey</subject><subject>Türkiye</subject><subject>Viral matriks proteinleri</subject><subject>Viral Matrix Proteins</subject><subject>Viruses</subject><subject>Virüsler</subject><issn>1300-7777</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><recordid>eNo9kLFOwzAQhjOAaCm8AULeKEOk2E7seISqUKRUdChsKDo7DpjGSbCToW-PqxZuOZ2-737p7iyaYpokMQ81iS69_04SkjOSXEQTwglLE8an0cey94M2bfwIzqF340aPChh0O6C1ttJBq9HGdQcFYTQv1psY36MwrLrqc2fau6Dvbf_VWUAbGExY9Ae8Hd1O76-i8xoar69PfRa9PS23i1VcvD6_LB6KuMdplsUSM8grTZTkgmV5zbWWVNUUhOJY1EpVkALGAUmV5yCJEsBphWXGlWAE6Cy6OeaODeyksWXvjAW3LzFjNAt4fsS9635G7YfSGq9004TrutGXmIs0ZTlPRVBvT-oora7-g_4-Rn8B8QNlFw</recordid><startdate>20010605</startdate><enddate>20010605</enddate><creator>Ataoğlu, Ö</creator><creator>Fen, T</creator><creator>Süer, Ö</creator><creator>Dağlı, M</creator><creator>Akı, Z</creator><creator>Yamaç, K</creator><general>Türk Hematoloji Derneği</general><scope>NPM</scope><scope>7X8</scope><scope>GIY</scope><scope>GIZ</scope><scope>GJA</scope><scope>GJB</scope></search><sort><creationdate>20010605</creationdate><title>Epstein-Barr Virus Latent Membrane Protein 1 (LMP-1) in Hodgkin's Lymphoma Patients in Turkey</title><author>Ataoğlu, Ö ; Fen, T ; Süer, Ö ; Dağlı, M ; Akı, Z ; Yamaç, K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p1455-b16a8de2cb79658f7eeb3cf3a9c719fccda4a11658bc88ab2c9a73d1b57c962a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Epstein-Barr Virus Infections</topic><topic>Epstein-barr virüs enfeksiyonları</topic><topic>Herpesvirus 4, Human</topic><topic>Herpesvirüs 4, insan</topic><topic>Lenfom</topic><topic>Lymphoma</topic><topic>Neoplasms</topic><topic>Neoplazmlar</topic><topic>Turkey</topic><topic>Türkiye</topic><topic>Viral matriks proteinleri</topic><topic>Viral Matrix Proteins</topic><topic>Viruses</topic><topic>Virüsler</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ataoğlu, Ö</creatorcontrib><creatorcontrib>Fen, T</creatorcontrib><creatorcontrib>Süer, Ö</creatorcontrib><creatorcontrib>Dağlı, M</creatorcontrib><creatorcontrib>Akı, Z</creatorcontrib><creatorcontrib>Yamaç, K</creatorcontrib><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>ULAKBIM - Mühendislik ve Temel Bilimler Veri Tabani</collection><collection>ULAKBIM - Yaşam Bilimleri Veri Tabani</collection><collection>ULAKBIM - Turk Sosyal Bilimler Veri Tabani</collection><collection>ULAKBIM - Türk Tıp Veri Tabani</collection><jtitle>Turkish journal of haematology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ataoğlu, Ö</au><au>Fen, T</au><au>Süer, Ö</au><au>Dağlı, M</au><au>Akı, Z</au><au>Yamaç, K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Epstein-Barr Virus Latent Membrane Protein 1 (LMP-1) in Hodgkin's Lymphoma Patients in Turkey</atitle><jtitle>Turkish journal of haematology</jtitle><addtitle>Turk J Haematol</addtitle><date>2001-06-05</date><risdate>2001</risdate><volume>18</volume><issue>2</issue><spage>123</spage><epage>126</epage><pages>123-126</pages><issn>1300-7777</issn><abstract>Epstein-Barr virus (EBV) has been implicated as a contributing factor in the development of Hodgkin's lymphoma. The aim of this study was to elucidate the association of Hodgkin's lymphoma with EBV in a Turkish population using immunohistochemical detection of LMP-1. We studied a total of 21 consecutive cases of Hodgkin's lymphoma from Turkey. LMP-1 protein was detected in 9 of 21 (42.8%) cases. LMP-1 was positive in 4 of 7 (57%) mixed cellularity and 5 of 13 (38.4%) nodular sclerosis subtype. The results of the current study suggests a strong association of Epstein-Barr virus with Hodgkin's lymphoma in Turkey and, together with those reported previously showed that Epstein-Barr virus correlated with mixed cellular type, with a slight male predominancy while there was no correlation with age.</abstract><cop>Turkey</cop><pub>Türk Hematoloji Derneği</pub><pmid>27264067</pmid><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1300-7777 |
| ispartof | Turkish journal of haematology, 2001-06, Vol.18 (2), p.123-126 |
| issn | 1300-7777 |
| language | eng |
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| source | DOAJ Directory of Open Access Journals |
| subjects | Epstein-Barr Virus Infections Epstein-barr virüs enfeksiyonları Herpesvirus 4, Human Herpesvirüs 4, insan Lenfom Lymphoma Neoplasms Neoplazmlar Turkey Türkiye Viral matriks proteinleri Viral Matrix Proteins Viruses Virüsler |
| title | Epstein-Barr Virus Latent Membrane Protein 1 (LMP-1) in Hodgkin's Lymphoma Patients in Turkey |
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