Giant cell reparative granuloma of the axis
Giant cell reparative granuloma (GCRG) is a rare, benign fibroosseous lesion. It typically arises in the mandible and maxilla, and less frequently in the skull bones. We report a case of GCRG of the axis, which is the first to be reported in the literature. A 35-year-old man was admitted to our clin...
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| Veröffentlicht in: | Turkish neurosurgery 2009-10, Vol.19 (4), p.423-427 |
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| container_title | Turkish neurosurgery |
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| creator | Bayar, Mehmet Akif Erdem, Yavuz Gokcek, Cevdet Koktekir, Ender Kilic, Celal Yasitli, Ugur Tekiner, Ayhan |
| description | Giant cell reparative granuloma (GCRG) is a rare, benign fibroosseous lesion. It typically arises in the mandible and maxilla, and less frequently in the skull bones. We report a case of GCRG of the axis, which is the first to be reported in the literature. A 35-year-old man was admitted to our clinic with the complaint of pain at his neck. There was no neurological deficit. CT and MRI showed a lesion destructing the body of the axis. Biopsy specimens were taken through the transoral-transpharyngeal route. Histopathological diagnosis was GCRG. The lesion was removed subtotally by the same route. We filled the tumor cavity with a bone graft and the patient was discharged with a halo brace without any neurological deficits. The follow-up CT revealed one year after the surgery showed sclerosis at the tumor site. The etiopathogenesis of GCRG is still controversial and the differential diagnosis, especially from giant cell tumor of bone is quite difficult. The treatment of choice for these lesions is complete surgical removal. Some authors recommend radiotherapy if total removal fails. |
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It typically arises in the mandible and maxilla, and less frequently in the skull bones. We report a case of GCRG of the axis, which is the first to be reported in the literature. A 35-year-old man was admitted to our clinic with the complaint of pain at his neck. There was no neurological deficit. CT and MRI showed a lesion destructing the body of the axis. Biopsy specimens were taken through the transoral-transpharyngeal route. Histopathological diagnosis was GCRG. The lesion was removed subtotally by the same route. We filled the tumor cavity with a bone graft and the patient was discharged with a halo brace without any neurological deficits. The follow-up CT revealed one year after the surgery showed sclerosis at the tumor site. The etiopathogenesis of GCRG is still controversial and the differential diagnosis, especially from giant cell tumor of bone is quite difficult. The treatment of choice for these lesions is complete surgical removal. Some authors recommend radiotherapy if total removal fails.</description><identifier>ISSN: 1019-5149</identifier><identifier>PMID: 19847766</identifier><language>eng</language><publisher>Turkey: Turkısh Neurosurgery Socıety</publisher><subject>Adult ; Axis, Cervical Vertebra - diagnostic imaging ; Axis, Cervical Vertebra - pathology ; Axis, Cervical Vertebra - surgery ; Biopsy ; Granuloma, Giant Cell - diagnostic imaging ; Granuloma, Giant Cell - pathology ; Granuloma, Giant Cell - surgery ; Humans ; Magnetic Resonance Imaging ; Male ; Recurrence ; Spinal Diseases - diagnostic imaging ; Spinal Diseases - pathology ; Spinal Diseases - surgery ; Tomography, X-Ray Computed</subject><ispartof>Turkish neurosurgery, 2009-10, Vol.19 (4), p.423-427</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19847766$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bayar, Mehmet Akif</creatorcontrib><creatorcontrib>Erdem, Yavuz</creatorcontrib><creatorcontrib>Gokcek, Cevdet</creatorcontrib><creatorcontrib>Koktekir, Ender</creatorcontrib><creatorcontrib>Kilic, Celal</creatorcontrib><creatorcontrib>Yasitli, Ugur</creatorcontrib><creatorcontrib>Tekiner, Ayhan</creatorcontrib><title>Giant cell reparative granuloma of the axis</title><title>Turkish neurosurgery</title><addtitle>Turk Neurosurg</addtitle><description>Giant cell reparative granuloma (GCRG) is a rare, benign fibroosseous lesion. It typically arises in the mandible and maxilla, and less frequently in the skull bones. We report a case of GCRG of the axis, which is the first to be reported in the literature. A 35-year-old man was admitted to our clinic with the complaint of pain at his neck. There was no neurological deficit. CT and MRI showed a lesion destructing the body of the axis. Biopsy specimens were taken through the transoral-transpharyngeal route. Histopathological diagnosis was GCRG. The lesion was removed subtotally by the same route. We filled the tumor cavity with a bone graft and the patient was discharged with a halo brace without any neurological deficits. The follow-up CT revealed one year after the surgery showed sclerosis at the tumor site. The etiopathogenesis of GCRG is still controversial and the differential diagnosis, especially from giant cell tumor of bone is quite difficult. The treatment of choice for these lesions is complete surgical removal. Some authors recommend radiotherapy if total removal fails.</description><subject>Adult</subject><subject>Axis, Cervical Vertebra - diagnostic imaging</subject><subject>Axis, Cervical Vertebra - pathology</subject><subject>Axis, Cervical Vertebra - surgery</subject><subject>Biopsy</subject><subject>Granuloma, Giant Cell - diagnostic imaging</subject><subject>Granuloma, Giant Cell - pathology</subject><subject>Granuloma, Giant Cell - surgery</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Recurrence</subject><subject>Spinal Diseases - diagnostic imaging</subject><subject>Spinal Diseases - pathology</subject><subject>Spinal Diseases - surgery</subject><subject>Tomography, X-Ray Computed</subject><issn>1019-5149</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFjz9PwzAUxD2AaGn5CCBvDCiSX-049ogqaJEqsdA5ekmewZB_2AmCb09QI7HcDb_Tne6MLUGATVJQdsEuY3wXQusNwAVbgDUqy7Resrudx3bgJdU1D9RjwMF_EX8N2I511yDvHB_eiOO3j2t27rCOdDX7ih0fH162--TwvHva3h-SHvRmSKxQmVQOjKxKhVSmoqxcJREKbbVFdMalRpLR5KggY7JUTwDBGVK6NEau2PWpd6zxo_BN3gffYPjJAVQKYuK3J96H7nOkOOSNj38PsKVujPm0LuwkdkrezMmxaKj6L5r_y18l7FQl</recordid><startdate>20091001</startdate><enddate>20091001</enddate><creator>Bayar, Mehmet Akif</creator><creator>Erdem, Yavuz</creator><creator>Gokcek, Cevdet</creator><creator>Koktekir, Ender</creator><creator>Kilic, Celal</creator><creator>Yasitli, Ugur</creator><creator>Tekiner, Ayhan</creator><general>Turkısh Neurosurgery Socıety</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>GIY</scope><scope>GIZ</scope><scope>GJA</scope><scope>GJB</scope></search><sort><creationdate>20091001</creationdate><title>Giant cell reparative granuloma of the axis</title><author>Bayar, Mehmet Akif ; Erdem, Yavuz ; Gokcek, Cevdet ; Koktekir, Ender ; Kilic, Celal ; Yasitli, Ugur ; Tekiner, Ayhan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p162t-904734f183dc4aec50cdfd3a1b6969aaf8f583e86efebe88756696a1f8e46c883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult</topic><topic>Axis, Cervical Vertebra - diagnostic imaging</topic><topic>Axis, Cervical Vertebra - pathology</topic><topic>Axis, Cervical Vertebra - surgery</topic><topic>Biopsy</topic><topic>Granuloma, Giant Cell - diagnostic imaging</topic><topic>Granuloma, Giant Cell - pathology</topic><topic>Granuloma, Giant Cell - surgery</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Recurrence</topic><topic>Spinal Diseases - diagnostic imaging</topic><topic>Spinal Diseases - pathology</topic><topic>Spinal Diseases - surgery</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bayar, Mehmet Akif</creatorcontrib><creatorcontrib>Erdem, Yavuz</creatorcontrib><creatorcontrib>Gokcek, Cevdet</creatorcontrib><creatorcontrib>Koktekir, Ender</creatorcontrib><creatorcontrib>Kilic, Celal</creatorcontrib><creatorcontrib>Yasitli, Ugur</creatorcontrib><creatorcontrib>Tekiner, Ayhan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>ULAKBIM - Mühendislik ve Temel Bilimler Veri Tabani</collection><collection>ULAKBIM - Yaşam Bilimleri Veri Tabani</collection><collection>ULAKBIM - Turk Sosyal Bilimler Veri Tabani</collection><collection>ULAKBIM - Türk Tıp Veri Tabani</collection><jtitle>Turkish neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bayar, Mehmet Akif</au><au>Erdem, Yavuz</au><au>Gokcek, Cevdet</au><au>Koktekir, Ender</au><au>Kilic, Celal</au><au>Yasitli, Ugur</au><au>Tekiner, Ayhan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Giant cell reparative granuloma of the axis</atitle><jtitle>Turkish neurosurgery</jtitle><addtitle>Turk Neurosurg</addtitle><date>2009-10-01</date><risdate>2009</risdate><volume>19</volume><issue>4</issue><spage>423</spage><epage>427</epage><pages>423-427</pages><issn>1019-5149</issn><abstract>Giant cell reparative granuloma (GCRG) is a rare, benign fibroosseous lesion. It typically arises in the mandible and maxilla, and less frequently in the skull bones. We report a case of GCRG of the axis, which is the first to be reported in the literature. A 35-year-old man was admitted to our clinic with the complaint of pain at his neck. There was no neurological deficit. CT and MRI showed a lesion destructing the body of the axis. Biopsy specimens were taken through the transoral-transpharyngeal route. Histopathological diagnosis was GCRG. The lesion was removed subtotally by the same route. We filled the tumor cavity with a bone graft and the patient was discharged with a halo brace without any neurological deficits. The follow-up CT revealed one year after the surgery showed sclerosis at the tumor site. The etiopathogenesis of GCRG is still controversial and the differential diagnosis, especially from giant cell tumor of bone is quite difficult. The treatment of choice for these lesions is complete surgical removal. Some authors recommend radiotherapy if total removal fails.</abstract><cop>Turkey</cop><pub>Turkısh Neurosurgery Socıety</pub><pmid>19847766</pmid><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Axis, Cervical Vertebra - diagnostic imaging Axis, Cervical Vertebra - pathology Axis, Cervical Vertebra - surgery Biopsy Granuloma, Giant Cell - diagnostic imaging Granuloma, Giant Cell - pathology Granuloma, Giant Cell - surgery Humans Magnetic Resonance Imaging Male Recurrence Spinal Diseases - diagnostic imaging Spinal Diseases - pathology Spinal Diseases - surgery Tomography, X-Ray Computed |
| title | Giant cell reparative granuloma of the axis |
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