Cystic splenic hamartoma with prominent endothelial proliferation mimicking malignancy: a case report

Splenic hamartoma is an uncommon benign lesion and usually determined incidentally. A 44-year-old female patient admitted with abdominal pain. There was not any history of trauma. During the ultrasonographic examination a cystic mass was seen in the upper pole of the spleen. Only anemia was detected biochemically, and all other laboratory findings were normal. The patient underent splenectomy. Grossly, a cystic mass including solid component was seen in the upper pole of the spleen. Histopathologically, cystic component did not have lining epithelium. Solid component included sinus like clefts, broad cordons and areas of prominent endothelial proliferation. The lesion was diagnosed as hamartoma. In this report, the clinical and histopathological features of a case of splenic hamartoma with prominent endothelial proliferation that may be easily confused with malignancy is presented.