The influence of established genetic variation in the haemostatic system on clinical restenosis after percutaneous coronary interventions

Summary Since activation of the haemostatic system is an important feature of the wound healing response triggered by arterial injury, variations in genes involved in thrombus formation may play a role in restenosis after percutaneous coronary interventions (PCI). Therefore, our aim was to examine t...

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Veröffentlicht in:	Thrombosis and haemostasis 2007-12, Vol.98 (6), p.1323-1328
Hauptverfasser:	Pons, Douwe, Monraats, Pascalle S., de Maat, Moniek P. M., Pires, Nuno M. M., Quax, Paul H. A., van Vlijmen, Bart J. M., Rosendaal, Frits R., Zwinderman, Aeilko H., Doevendans, Pieter A. F. M., Waltenberger, Johannes, de Winter, Robbert J., Tio, René A., Frants, Rune R., van der Laarse, Arnoud, Vander Wall, Ernst E., Jukema, Wouter J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Angioplasty, Balloon, Coronary - adverse effects Biological and medical sciences Blood coagulation. Blood cells Cardiovascular Biology and Cell Signalling Coagulation factors Coronary Restenosis - blood Coronary Restenosis - genetics Coronary Stenosis - genetics Coronary Stenosis - therapy Diabetes Complications - genetics Factor V - genetics Factor VII - genetics Female Follow-Up Studies Fundamental and applied biological sciences. Psychology Genetic Predisposition to Disease Hematologic and hematopoietic diseases Hemostasis - genetics Heterozygote Homozygote Humans Male Medical sciences Middle Aged Molecular and cellular biology Netherlands Phenotype Plasminogen Activator Inhibitor 1 - genetics Platelet diseases and coagulopathies Polymorphism, Genetic polymorphisms Proportional Hazards Models Prospective Studies Prothrombin - genetics Research Design Restenosis Risk Assessment Risk Factors Smoking - adverse effects Time Factors Treatment Outcome
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