Protein-Malnutrition bei pädiatrischen Patienten mit onkologischen Erkrankungen
Abstract To study the frequency of protein-caloric malnutrition in children (n = 16) with malignant diseases, we measured serum-albumin, -transferrin, -prealbumin and -retinol-binding protein (Radial immunodiffusion) before treatment was started. In 9 children at least 3 of the 4 rapid-turnover prot...
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| Veröffentlicht in: | Klinische Pädiatrie 1987-03, Vol.199 (2), p.73-76 |
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| container_title | Klinische Pädiatrie |
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| creator | Howanietz, H. Thun-Hohenstein, L. Haschke, F. Pietschnig, B. Bruckner, R. Camaya, Z. Jürgenssen, O. A. |
| description | Abstract
To study the frequency of protein-caloric malnutrition in children (n = 16) with malignant diseases, we measured serum-albumin, -transferrin, -prealbumin and -retinol-binding protein (Radial immunodiffusion) before treatment was started. In 9 children at least 3 of the 4 rapid-turnover proteins were below the age-specific reference values. 7 patients (44 %) with low rapid turnover proteins were free from infection, liver and renal dysfunction and thus, diagnosis of protein-caloric malnutrition was established. Anthropometric parameters as weight for age and the weight/height ratio did not predict protein-caloric malnutrition. Nutritional therapy (enteral, parenteral) during a period of 2 weeks resulted in significant increase of albumin (p < 0.05), prealbumin (p < 0.01) and retinol-binding protein (p < 0.01). Rapid turnover proteins can be easily measured in each laboratory and are useful in diagnosis and treatment of protein-caloric malnutrition of children with malignant diseases as long as the limitations of this method are not neglected. |
| doi_str_mv | 10.1055/s-2008-1026765 |
| format | Article |
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To study the frequency of protein-caloric malnutrition in children (n = 16) with malignant diseases, we measured serum-albumin, -transferrin, -prealbumin and -retinol-binding protein (Radial immunodiffusion) before treatment was started. In 9 children at least 3 of the 4 rapid-turnover proteins were below the age-specific reference values. 7 patients (44 %) with low rapid turnover proteins were free from infection, liver and renal dysfunction and thus, diagnosis of protein-caloric malnutrition was established. Anthropometric parameters as weight for age and the weight/height ratio did not predict protein-caloric malnutrition. Nutritional therapy (enteral, parenteral) during a period of 2 weeks resulted in significant increase of albumin (p < 0.05), prealbumin (p < 0.01) and retinol-binding protein (p < 0.01). Rapid turnover proteins can be easily measured in each laboratory and are useful in diagnosis and treatment of protein-caloric malnutrition of children with malignant diseases as long as the limitations of this method are not neglected.</description><identifier>ISSN: 0300-8630</identifier><identifier>EISSN: 1439-3824</identifier><identifier>DOI: 10.1055/s-2008-1026765</identifier><language>ger</language><subject>ORIGINALIEN</subject><ispartof>Klinische Pädiatrie, 1987-03, Vol.199 (2), p.73-76</ispartof><rights>Georg Thieme Verlag KG Stuttgart · New York</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c835-2e994042402ca5998988d815abd8cfc65a9d6de13ee32141b9fd14f3a2b3cbfd3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2008-1026765.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><link.rule.ids>314,776,780,3004,27903,27904,54537</link.rule.ids></links><search><creatorcontrib>Howanietz, H.</creatorcontrib><creatorcontrib>Thun-Hohenstein, L.</creatorcontrib><creatorcontrib>Haschke, F.</creatorcontrib><creatorcontrib>Pietschnig, B.</creatorcontrib><creatorcontrib>Bruckner, R.</creatorcontrib><creatorcontrib>Camaya, Z.</creatorcontrib><creatorcontrib>Jürgenssen, O. A.</creatorcontrib><title>Protein-Malnutrition bei pädiatrischen Patienten mit onkologischen Erkrankungen</title><title>Klinische Pädiatrie</title><addtitle>Klin Padiatr</addtitle><description>Abstract
To study the frequency of protein-caloric malnutrition in children (n = 16) with malignant diseases, we measured serum-albumin, -transferrin, -prealbumin and -retinol-binding protein (Radial immunodiffusion) before treatment was started. In 9 children at least 3 of the 4 rapid-turnover proteins were below the age-specific reference values. 7 patients (44 %) with low rapid turnover proteins were free from infection, liver and renal dysfunction and thus, diagnosis of protein-caloric malnutrition was established. Anthropometric parameters as weight for age and the weight/height ratio did not predict protein-caloric malnutrition. Nutritional therapy (enteral, parenteral) during a period of 2 weeks resulted in significant increase of albumin (p < 0.05), prealbumin (p < 0.01) and retinol-binding protein (p < 0.01). Rapid turnover proteins can be easily measured in each laboratory and are useful in diagnosis and treatment of protein-caloric malnutrition of children with malignant diseases as long as the limitations of this method are not neglected.</description><subject>ORIGINALIEN</subject><issn>0300-8630</issn><issn>1439-3824</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNotkEtOwzAYhC0EEqGwZZ0LGH6_gr1EVXlIRWTRveXETusmtVHs3IibcDFSNasZzUgz0ofQI4EnAkI8J0wBJCZAq5dKXKGCcKYwk5RfowIYAJYVg1t0l9IRgHAFqkB1PcbsfMBfZghTHn32MZSN8-XP36_1Zk5Se3ChrE32LuTZnXwuY-jjEPdLtxn70YR-CnsX7tFNZ4bkHhZdod3bZrf-wNvv98_16xa3kglMnVIcOOVAWyOUkkpKK4kwjZVt11bCKFtZR5hzjBJOGtVZwjtmaMPaprNshfBlNh-8Ozl9jNMY5j9NQJ9p6KTPNPRCg_0DattUxg</recordid><startdate>198703</startdate><enddate>198703</enddate><creator>Howanietz, H.</creator><creator>Thun-Hohenstein, L.</creator><creator>Haschke, F.</creator><creator>Pietschnig, B.</creator><creator>Bruckner, R.</creator><creator>Camaya, Z.</creator><creator>Jürgenssen, O. A.</creator><scope/></search><sort><creationdate>198703</creationdate><title>Protein-Malnutrition bei pädiatrischen Patienten mit onkologischen Erkrankungen</title><author>Howanietz, H. ; Thun-Hohenstein, L. ; Haschke, F. ; Pietschnig, B. ; Bruckner, R. ; Camaya, Z. ; Jürgenssen, O. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c835-2e994042402ca5998988d815abd8cfc65a9d6de13ee32141b9fd14f3a2b3cbfd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>ger</language><creationdate>1987</creationdate><topic>ORIGINALIEN</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Howanietz, H.</creatorcontrib><creatorcontrib>Thun-Hohenstein, L.</creatorcontrib><creatorcontrib>Haschke, F.</creatorcontrib><creatorcontrib>Pietschnig, B.</creatorcontrib><creatorcontrib>Bruckner, R.</creatorcontrib><creatorcontrib>Camaya, Z.</creatorcontrib><creatorcontrib>Jürgenssen, O. A.</creatorcontrib><jtitle>Klinische Pädiatrie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Howanietz, H.</au><au>Thun-Hohenstein, L.</au><au>Haschke, F.</au><au>Pietschnig, B.</au><au>Bruckner, R.</au><au>Camaya, Z.</au><au>Jürgenssen, O. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Protein-Malnutrition bei pädiatrischen Patienten mit onkologischen Erkrankungen</atitle><jtitle>Klinische Pädiatrie</jtitle><addtitle>Klin Padiatr</addtitle><date>1987-03</date><risdate>1987</risdate><volume>199</volume><issue>2</issue><spage>73</spage><epage>76</epage><pages>73-76</pages><issn>0300-8630</issn><eissn>1439-3824</eissn><abstract>Abstract
To study the frequency of protein-caloric malnutrition in children (n = 16) with malignant diseases, we measured serum-albumin, -transferrin, -prealbumin and -retinol-binding protein (Radial immunodiffusion) before treatment was started. In 9 children at least 3 of the 4 rapid-turnover proteins were below the age-specific reference values. 7 patients (44 %) with low rapid turnover proteins were free from infection, liver and renal dysfunction and thus, diagnosis of protein-caloric malnutrition was established. Anthropometric parameters as weight for age and the weight/height ratio did not predict protein-caloric malnutrition. Nutritional therapy (enteral, parenteral) during a period of 2 weeks resulted in significant increase of albumin (p < 0.05), prealbumin (p < 0.01) and retinol-binding protein (p < 0.01). Rapid turnover proteins can be easily measured in each laboratory and are useful in diagnosis and treatment of protein-caloric malnutrition of children with malignant diseases as long as the limitations of this method are not neglected.</abstract><doi>10.1055/s-2008-1026765</doi><tpages>4</tpages></addata></record> |
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| language | ger |
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| subjects | ORIGINALIEN |
| title | Protein-Malnutrition bei pädiatrischen Patienten mit onkologischen Erkrankungen |
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