Novel Synthesis and Anti-HIV-1 Activity of 2-Arylthio-6-benzyl-2,3-dihydro-1H-pyrimidin-4-ones (Aryl S-DABOs)

ABSTRACT The synthesis and the anti-HIV-1 activity of a series of 2-arylthio-6-benzyl-2,3-dihydro-1H-pyrimidin-4-ones (aryl S-DABOs) are reported. These compounds were synthesized via a coupling reaction of the corresponding 6-benzyl-2-thiouracils with aryl iodides in the presence of neocuproine hyd...

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Veröffentlicht in:Synthesis (Stuttgart) 2007-07, Vol.2007 (13), p.1955-1960
Hauptverfasser: Aly, Youssef L., Pedersen, Erik B., La Colla, Paolo, Loddo, Roberta
Format: Artikel
Sprache:eng
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