Pyridinium Ylides in the Synthesis of 2,3-Dihydrofurans

ABSTRACT A new method for the synthesis of 2,3-dihydrofurans from readily available starting enones and pyridinium salts has been developed. This protocol can provide a novel and effective methodology for the preparation of 2,3-dihydrofurans in a stereoselective fashion. To increase the efficiency o...

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Veröffentlicht in:Synthesis (Stuttgart) 2006-02, Vol.2006 (4), p.675-679
Hauptverfasser: Chuang, Che-Ping, Tsai, An-I
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Tsai, An-I
description ABSTRACT A new method for the synthesis of 2,3-dihydrofurans from readily available starting enones and pyridinium salts has been developed. This protocol can provide a novel and effective methodology for the preparation of 2,3-dihydrofurans in a stereoselective fashion. To increase the efficiency of this reaction the one-pot process was also developed, in which the pyridinium salts were generated in situ from corresponding halides.
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title Pyridinium Ylides in the Synthesis of 2,3-Dihydrofurans
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