Role of the Leucine-Rich Domain of Platelet GPIbα in Correct Post-translational Processing - The Nancy I Bernard-Soulier Mutation Expressed on CHO Cells

Summary The mechanisms governing the biosynthesis and surface expression of platelet adhesive receptors on parent megakaryocytes are as yet poorly understood. In particular, the assembly and processing of the multisubunit glycoprotein (GP) Ib-IX-V complex, a receptor for von Willebrand factor (vWf)...

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Veröffentlicht in:	Thrombosis and haemostasis 2000, Vol.84 (1), p.104-111
Hauptverfasser:	Ulsemer, Philippe, Lanza, François, Baas, Marie-Jeanne, Schwartz, Agnès, Ravanat, Catherine, Briquel, Marie-Elisabeth, Cranmer, Sue, Jackson, Shaun, Cazenave, Jean-Pierre, de la Salle, Corinne
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Commentary Hematologic and hematopoietic diseases Medical sciences Platelet diseases and coagulopathies
Online-Zugang:	Volltext
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