Accelerated thrombolysis in a rabbit model of carotid artery thrombosis with liposome-encapsulated and microencapsulated streptokinase

Summary The present study compares the efficacy of two formulations of encapsulated streptokinase to streptokinase in a rabbit model of carotid artery thrombosis. Arterial thrombosis followed the injection of thrombin mixed with autologous whole blood into a carotid artery of New Zealand white rabbi...

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Veröffentlicht in:	Thrombosis and haemostasis 2003-07, Vol.90 (1), p.64-70
Hauptverfasser:	Leach, J. Kent, O’Rear, Edgar A., Patterson, Eugene, Miao, Yiwei, Johnson, Arthur E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Coagulation, Fibrinolysis and Cellular Haemostasis Blood. Blood coagulation. Reticuloendothelial system Carotid Artery Thrombosis - drug therapy Drug Carriers Drug Compounding Drug Evaluation, Preclinical Female Fibrinolytic Agents - administration & dosage Fibrinolytic Agents - therapeutic use Liposomes Male Medical sciences Microspheres Models, Animal Pharmacology. Drug treatments Polyethylene Glycols Rabbits Recurrence Streptokinase - administration & dosage Streptokinase - therapeutic use Thrombin - toxicity Thrombolytic Therapy
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