Belimumab concentration measurements using a homologous anti-idiotype immunoassay

Monitoring belimumab concentrations in patients can be a valuable tool for assessing treatment response and for personalizing drug doses. Various assay formats may be used to measure concentrations of therapeutic monoclonal antibodies. A particularly useful format involves the use of anti-idiotype m...

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Veröffentlicht in:	Journal of immunological methods 2024-09, Vol.532, p.113717, Article 113717
Hauptverfasser:	Loeff, Floris C., Parodis, Ioannis, Walhelm, Tomas, Jönsen, Andreas, Nikolopoulos, Dionysis, Sjöwall, Christopher, Bengtsson, Anders A., Kos, Dorien, van Leeuwen, Astrid, van den Broek, Bryan, Dijk, Lisanne, Jeremiasse, Jorn, Blomjous, Birgit S., Voskuyl, Alexandre E., Wolbink, Gerrit Jan, Bultink, Irene E.M., Rispens, Theo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-idiotype antibodies antibodies Antibodies, Anti-Idiotypic - immunology Antibodies, Monoclonal, Humanized - immunology Antibodies, Monoclonal, Humanized - therapeutic use Belimumab Biochemistry and Molecular Biology Biokemi och molekylärbiologi Biologi Biological Sciences Drug Monitoring - methods drugs enzyme-linked immunosorbent assay Enzyme-Linked Immunosorbent Assay - methods Humans Immunosuppressive Agents - blood Natural Sciences Naturvetenskap PK/ADA assays Rabbit monoclonal antibodies therapeutics
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