Integrating single-cell multi-omics and prior biological knowledge for a functional characterization of the immune system

The immune system comprises diverse specialized cell types that cooperate to defend the host against a wide range of pathogenic threats. Recent advancements in single-cell and spatial multi-omics technologies provide rich information about the molecular state of immune cells. Here, we review how the...

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Veröffentlicht in:Nature immunology 2024-03, Vol.25 (3), p.405-417
Hauptverfasser: Schäfer, Philipp Sven Lars, Dimitrov, Daniel, Villablanca, Eduardo J., Saez-Rodriguez, Julio
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Sprache:eng
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