Genetic contribution of reproductive traits to risk of uterine leiomyomata: a large-scale, genome-wide, cross-trait analysis

Although phenotypic associations between female reproductive characteristics and uterine leiomyomata have long been observed in epidemiologic investigations, the shared genetic architecture underlying these complex phenotypes remains unclear. We aimed to investigate the shared genetic basis, pleiotr...

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Veröffentlicht in:	American journal of obstetrics and gynecology 2024-04, Vol.230 (4), p.438.e1-438.e15
Hauptverfasser:	Xiao, Changfeng, Wu, Xueyao, Gallagher, C. Scott, Rasooly, Danielle, Jiang, Xia, Morton, Cynthia Casson
Format:	Artikel
Sprache:	eng
Schlagworte:	age at first birth age at menarche age at natural menopause causal relationship genetic correlation pleiotropic effect uterine leiomyomata
Online-Zugang:	Volltext
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