Reactivity of β-Carbolines and Cyclopenta[b]indolones Prepared from the Intramolecular Cyclization of 5(4H)-Oxazolones Derived from L-Tryptophan

4‐(1H‐Indol‐3‐ylmethyl)‐2‐trichloromethyl‐1,3‐oxazol‐5(4H)‐one (4) was shown to undergo an intramolecular reaction in the presence of TFA, to afford a β‐carboline 5 and a cyclopenta[b]indolone 6 by nucleophilic addition at C‐2 and C‐5, respectively. The distribution of these two products was found t...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	European journal of organic chemistry 2004-03, Vol.2004 (6), p.1286-1297
Hauptverfasser:	Condie, Glenn C., Bergman, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	5(4H)-Oxazolone Bischler−Napieralski reaction Canthine Cyclization Cyclopenta[b]indolone Medicin och hälsovetenskap Synthesis design β-Carboline
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!