Synthesis of Sulfonimidamide‐Based Amino Acid Building Blocks with Orthogonal Protecting Groups

Herein, we report the synthesis of novel sulfonimidamides (SIAs) based on amino acid building blocks using a one‐pot method from tert‐butyldiphenylsilyl‐protected (TBDPS) sulfonamides, as well as exploration of orthogonal deprotection strategies. Among the several protecting groups investigated, TBD...

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Veröffentlicht in:	European journal of organic chemistry 2019-02, Vol.2019 (5), p.1045-1057
Hauptverfasser:	Chinthakindi, Praveen K., Benediktsdottir, Andrea, Ibrahim, Ayah, Wared, Atta, Aurell, Carl‐Johan, Pettersen, Anna, Zamaratski, Edouard, Arvidsson, Per I., Chen, Yantao, Sandström, Anja
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Chirality Esters Organic chemistry Peptidomimetics Protecting groups Sulfonamides Sulfonimidamides Synthesis
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