Mutations of the Novel Tumor Suppressor Gene SAMHD1 Are Frequent and Correlate with Decreased Protein Expression in Peripheral T-Cell Lymphomas (PTCL)

Introduction: The SAM domain and HD domain 1 (SAMHD1) protein is a deoxynucleoside triphosphate (dNTP) triphosphohydrolase, which depletes the intracellular dNTP substrates and thus protects the host (human) cells from replication of viruses such as HIV. Mutations of SAMHD1 gene have been linked to...

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Veröffentlicht in:	Blood 2021, Vol.138 (Supplement 1), p.3515-3515
Hauptverfasser:	Kokaraki, Georgia, Xagoraris, Ioanna, Farrajota Neves Da Silva, Pedro, Sutton, Lesley Ann, Maia Falcão, Raul, Estefano Santana de Souza, Jorge, Österborg, Anders, Wirta, Valtteri, Rosenquist Brandell, Richard, Rassidakis, Georgios Z.
Format:	Artikel
Sprache:	eng
Schlagworte:	Medicin och hälsovetenskap
Online-Zugang:	Volltext
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