Sirolimus (rapamycin)-based therapy in human renal transplantation : Similar efficacy and different toxicity compared with cyclosporine

Sirolimus (rapamycin) is a potent immunosuppressant with a mechanism of action different from cyclosporine (CsA) or tacrolimus. In 11 European centers, first cadaveric renal allograft recipients were randomized to CsA (n=42) or sirolimus (n=41). Dosing of these agents was concentration-controlled an...

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Veröffentlicht in:	Transplantation 1999-04, Vol.67 (7), p.1036-1042
Hauptverfasser:	GROTH, C. G, BÄCKMAN, L, WRAMNER, L, BRATTSTRÖM, C, CHARPENTIER, B, MORALES, J.-M, CALNE, R, KREIS, H, LANG, P, TOURAINE, J.-L, CLAESSON, K, CAMPISTOL, J. M, DURAND, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Immunomodulators Medical sciences Pharmacology. Drug treatments
Online-Zugang:	Volltext
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