In vitro analysis of the glucose-transport system in GLUT4-null skeletal muscle

We have characterized the glucose-transport system in soleus muscle from female GLUT4-null mice to determine whether GLUT1, 3 or 5 account for insulin-stimulated glucose-transport activity. Insulin increased 2-deoxyglucose uptake 2.8- and 2.1-fold in soleus muscle from wild-type and GLUT4-null mice,...

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Veröffentlicht in:	Biochemical journal 1999-09, Vol.342 ( Pt 2) (2), p.321-328
Hauptverfasser:	Ryder, J W, Kawano, Y, Chibalin, A V, Rincón, J, Tsao, T S, Stenbit, A E, Combatsiaris, T, Yang, J, Holman, G D, Charron, M J, Zierath, J R
Format:	Artikel
Sprache:	eng
Schlagworte:	3-O-Methylglucose - metabolism Affinity Labels Animals Azides Biological Transport, Active - drug effects Cell Membrane - metabolism Cytochalasin B - pharmacology Deoxyglucose - metabolism Disaccharides Female Gene Expression Glucose - metabolism Glucose Transporter Type 1 Glucose Transporter Type 3 Glucose Transporter Type 4 Glucose Transporter Type 5 Glycosides In Vitro Techniques Insulin - pharmacology Kinetics Medicin och hälsovetenskap Mice Mice, Inbred C57BL Mice, Inbred CBA Mice, Knockout Monosaccharide Transport Proteins - genetics Monosaccharide Transport Proteins - metabolism Muscle Proteins Muscle, Skeletal - drug effects Muscle, Skeletal - metabolism Nerve Tissue Proteins Propylamines
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