Tactile stimulation of the hand causes bilateral cortical activation: a functional magnetic resonance study in humans
The purpose of the present study was to assess the somatotopy of the cortical sensory representation of the fingers using a natural tactile stimulation of the glabrous skin. Multislice echoplanar imaging techniques were utilized to investigate blood oxygen level dependent (BOLD) signal changes as a...
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| Veröffentlicht in: | Neuroscience letters 1999-08, Vol.271 (1), p.29-32 |
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| creator | Hansson, Thomas Brismar, Tom |
| description | The purpose of the present study was to assess the somatotopy of the cortical sensory representation of the fingers using a natural tactile stimulation of the glabrous skin. Multislice echoplanar imaging techniques were utilized to investigate blood oxygen level dependent (BOLD) signal changes as a measure of cortical activation. Repetitive sensory stimulation of the glabrous skin of digit II–III and digit IV–V resulted in a multifocal signal increase in a restricted area near the central sulcus in the contralateral hemisphere with a considerable overlap between the activated areas of digit II–III and digit IV–V. In addition, in all subjects tactile stimulation resulted in ipsilateral signal increase near the central sulcus, which was 15–22% of the contralateral effect. Stimulation of digit II–III caused significantly (
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| doi_str_mv | 10.1016/S0304-3940(99)00508-X |
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P<0.05) more activated voxels than digit IV–V in the contralateral hemisphere for both hands and for the left hand in the ipsilateral hemisphere. These findings suggest an ipsilateral activation of the primary somatosensory cortex during a natural tactile stimulation of the digits in humans.</description><identifier>ISSN: 0304-3940</identifier><identifier>ISSN: 1872-7972</identifier><identifier>EISSN: 1872-7972</identifier><identifier>DOI: 10.1016/S0304-3940(99)00508-X</identifier><identifier>PMID: 10471206</identifier><identifier>CODEN: NELED5</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Adult ; Biological and medical sciences ; Brain Mapping ; Cerebral Cortex - physiology ; Digits ; Female ; Fingers - innervation ; Functional Laterality ; Functional magnetic resonance imaging ; Fundamental and applied biological sciences. Psychology ; Glabrous ; Human ; Humans ; Ipsilateral ; Magnetic Resonance Imaging - methods ; Male ; MEDICIN ; MEDICINE ; Oxygen - blood ; Physical Stimulation ; Sensory ; Skin - innervation ; Somatosensory ; Somatosensory Cortex - physiology ; Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors ; Tactile ; Touch - physiology ; Vertebrates: nervous system and sense organs</subject><ispartof>Neuroscience letters, 1999-08, Vol.271 (1), p.29-32</ispartof><rights>1999 Elsevier Science Ireland Ltd</rights><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c614t-e0196db19f49655519f3717990cd2fb41b3a9a0d113de266837eaad4fbcc09003</citedby><cites>FETCH-LOGICAL-c614t-e0196db19f49655519f3717990cd2fb41b3a9a0d113de266837eaad4fbcc09003</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S030439409900508X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1922243$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10471206$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-25067$$DView record from Swedish Publication Index$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:1930836$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Hansson, Thomas</creatorcontrib><creatorcontrib>Brismar, Tom</creatorcontrib><title>Tactile stimulation of the hand causes bilateral cortical activation: a functional magnetic resonance study in humans</title><title>Neuroscience letters</title><addtitle>Neurosci Lett</addtitle><description>The purpose of the present study was to assess the somatotopy of the cortical sensory representation of the fingers using a natural tactile stimulation of the glabrous skin. Multislice echoplanar imaging techniques were utilized to investigate blood oxygen level dependent (BOLD) signal changes as a measure of cortical activation. Repetitive sensory stimulation of the glabrous skin of digit II–III and digit IV–V resulted in a multifocal signal increase in a restricted area near the central sulcus in the contralateral hemisphere with a considerable overlap between the activated areas of digit II–III and digit IV–V. In addition, in all subjects tactile stimulation resulted in ipsilateral signal increase near the central sulcus, which was 15–22% of the contralateral effect. Stimulation of digit II–III caused significantly (
P<0.05) more activated voxels than digit IV–V in the contralateral hemisphere for both hands and for the left hand in the ipsilateral hemisphere. These findings suggest an ipsilateral activation of the primary somatosensory cortex during a natural tactile stimulation of the digits in humans.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Brain Mapping</subject><subject>Cerebral Cortex - physiology</subject><subject>Digits</subject><subject>Female</subject><subject>Fingers - innervation</subject><subject>Functional Laterality</subject><subject>Functional magnetic resonance imaging</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Glabrous</subject><subject>Human</subject><subject>Humans</subject><subject>Ipsilateral</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>MEDICIN</subject><subject>MEDICINE</subject><subject>Oxygen - blood</subject><subject>Physical Stimulation</subject><subject>Sensory</subject><subject>Skin - innervation</subject><subject>Somatosensory</subject><subject>Somatosensory Cortex - physiology</subject><subject>Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors</subject><subject>Tactile</subject><subject>Touch - physiology</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0304-3940</issn><issn>1872-7972</issn><issn>1872-7972</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUuLFDEQgIMo7rj6E5QcRBRsraTTycSLLOsTFjy4yt5COqneifZjTDor--9NzwyrF9lTiqqvHuQj5DGDVwyYfP0VahBVrQU81_oFQAPr6uIOWbG14pXSit8lqxvkiDxI6QcUijXiPjliIBTjIFckn1s3hx5pmsOQezuHaaRTR-cN0o0dPXU2J0y0DaWG0fbUTXEOrgRL49Wu4Q21tMujW-JSGOzliIWhEVNJjG6Znv01DSPd5MGO6SG519k-4aPDe0y-fXh_fvqpOvvy8fPpyVnlJBNzhcC09C3TndCyaZoS1IoprcF53rWCtbXVFjxjtUcu5bpWaK0XXescaID6mFT7uek3bnNrtjEMNl6byQZzSP0sERoJopYL__K__Lvw_cRM8dL0IRvegFQFf7bHt3H6lTHNZgjJYd_bEaecjCo_Lppy3W0gUwLUmtcFbPagi1NKEbubExiYxbvZeTeLVKO12Xk3F6XvyWFBbgf0_3TtRRfg6QGwqcjrYtES0l9Oc87Fsv_tHsNi5SpgNMkFLAZ9iOhm46dwyyV_AGRDzAQ</recordid><startdate>19990813</startdate><enddate>19990813</enddate><creator>Hansson, Thomas</creator><creator>Brismar, Tom</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>DG8</scope></search><sort><creationdate>19990813</creationdate><title>Tactile stimulation of the hand causes bilateral cortical activation: a functional magnetic resonance study in humans</title><author>Hansson, Thomas ; Brismar, Tom</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c614t-e0196db19f49655519f3717990cd2fb41b3a9a0d113de266837eaad4fbcc09003</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Brain Mapping</topic><topic>Cerebral Cortex - physiology</topic><topic>Digits</topic><topic>Female</topic><topic>Fingers - innervation</topic><topic>Functional Laterality</topic><topic>Functional magnetic resonance imaging</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Glabrous</topic><topic>Human</topic><topic>Humans</topic><topic>Ipsilateral</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>MEDICIN</topic><topic>MEDICINE</topic><topic>Oxygen - blood</topic><topic>Physical Stimulation</topic><topic>Sensory</topic><topic>Skin - innervation</topic><topic>Somatosensory</topic><topic>Somatosensory Cortex - physiology</topic><topic>Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors</topic><topic>Tactile</topic><topic>Touch - physiology</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hansson, Thomas</creatorcontrib><creatorcontrib>Brismar, Tom</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><collection>SwePub</collection><collection>SwePub Articles</collection><collection>SWEPUB Linköpings universitet</collection><jtitle>Neuroscience letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hansson, Thomas</au><au>Brismar, Tom</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tactile stimulation of the hand causes bilateral cortical activation: a functional magnetic resonance study in humans</atitle><jtitle>Neuroscience letters</jtitle><addtitle>Neurosci Lett</addtitle><date>1999-08-13</date><risdate>1999</risdate><volume>271</volume><issue>1</issue><spage>29</spage><epage>32</epage><pages>29-32</pages><issn>0304-3940</issn><issn>1872-7972</issn><eissn>1872-7972</eissn><coden>NELED5</coden><abstract>The purpose of the present study was to assess the somatotopy of the cortical sensory representation of the fingers using a natural tactile stimulation of the glabrous skin. Multislice echoplanar imaging techniques were utilized to investigate blood oxygen level dependent (BOLD) signal changes as a measure of cortical activation. Repetitive sensory stimulation of the glabrous skin of digit II–III and digit IV–V resulted in a multifocal signal increase in a restricted area near the central sulcus in the contralateral hemisphere with a considerable overlap between the activated areas of digit II–III and digit IV–V. In addition, in all subjects tactile stimulation resulted in ipsilateral signal increase near the central sulcus, which was 15–22% of the contralateral effect. Stimulation of digit II–III caused significantly (
P<0.05) more activated voxels than digit IV–V in the contralateral hemisphere for both hands and for the left hand in the ipsilateral hemisphere. These findings suggest an ipsilateral activation of the primary somatosensory cortex during a natural tactile stimulation of the digits in humans.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>10471206</pmid><doi>10.1016/S0304-3940(99)00508-X</doi><tpages>4</tpages></addata></record> |
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| ispartof | Neuroscience letters, 1999-08, Vol.271 (1), p.29-32 |
| issn | 0304-3940 1872-7972 1872-7972 |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Biological and medical sciences Brain Mapping Cerebral Cortex - physiology Digits Female Fingers - innervation Functional Laterality Functional magnetic resonance imaging Fundamental and applied biological sciences. Psychology Glabrous Human Humans Ipsilateral Magnetic Resonance Imaging - methods Male MEDICIN MEDICINE Oxygen - blood Physical Stimulation Sensory Skin - innervation Somatosensory Somatosensory Cortex - physiology Somesthesis and somesthetic pathways (proprioception, exteroception, nociception) interoception electrolocation. Sensory receptors Tactile Touch - physiology Vertebrates: nervous system and sense organs |
| title | Tactile stimulation of the hand causes bilateral cortical activation: a functional magnetic resonance study in humans |
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