Modulation of elastase binding to elastin by human alveolar macrophage-derived lipids

Human neutrophil elastase (HNE), an enzyme secreted by activated neutrophils, can bind to and degrade extracellular matrix including human lung elastin. This protease is believed to play an important role in several destructive processes including pulmonary emphysema. In this study, we hypothesized...

Ausführliche Beschreibung