Prognostic value of a CCR5 defective allele in pediatric HIV-1 infection

A deletion of 32 base pairs in the CCR5 gene (delta32 CCR5) has been linked to resistance to HIV-1 infection in exposed adults and to the delay of disease progression in infected adults. To determine the role of delta32 CCR5 in disease progression of HIV-1 infected children born to seropositive moth...

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Veröffentlicht in:	Molecular medicine (Cambridge, Mass.) Mass.), 2000-01, Vol.6 (1), p.28-36
Hauptverfasser:	Romiti, M L, Colognesi, C, Cancrini, C, Mas, A, Berrino, M, Salvatori, F, Orlandi, P, Jansson, M, Palomba, E, Plebani, A, Bertran, J M, Hernandez, M, de Martino, M, Amoroso, A, Tovo, P A, Rossi, P, Espanol, T, Scarlatti, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent AIDS/HIV Alleles Child Child, Preschool HIV Infections - genetics HIV Long-Term Survivors HIV-1 Humans Infant Infant, Newborn Infectious Disease Transmission, Vertical Jurkat Cells - virology Macrophages - virology Mutation Phenotype Predictive Value of Tests Prognosis Receptors, CCR5 - genetics Sequence Deletion
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