Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level

Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal disorders characterized by ineffective hematopoiesis and frequent progression to acute myeloid leukemia. Within MDS, 5q− syndrome constitutes a distinct clinical entity characterized by an isolated deletion of the long arm of chromo...

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Veröffentlicht in:Blood 2000-09, Vol.96 (6), p.2012-2021
Hauptverfasser: Nilsson, Lars, Åstrand-Grundström, Ingbritt, Arvidsson, Ingrid, Jacobsson, Björn, Hellström-Lindberg, Eva, Hast, Robert, Jacobsen, Sten E. W.
Format: Artikel
Sprache:eng
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