Lipoprotein Secretion and Triglyceride Stores in the Heart

The genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in mouse and human heart tissue. Why the heart would express these “lipoprotein assembly” genes has been unclear. Here we demonstrate that the beating mouse heart actually secretes spherical lipoproteins. Moreo...

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Veröffentlicht in:	The Journal of biological chemistry 2001-10, Vol.276 (42), p.38511-38517
Hauptverfasser:	Björkegren, Johan, Véniant, Murielle, Kim, Sun K., Withycombe, Shannon K., Wood, Philip A., Hellerstein, Marc K., Neese, Richard A., Young, Stephen G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Glucose - metabolism Blotting, Southern Cells, Cultured Humans Lipids - blood Lipoproteins - metabolism Liver - metabolism long-chain acyl-CoA dehydrogenase Medicin och hälsovetenskap Mice Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Microscopy, Electron microsomal triglyceride transfer protein Myocardium - metabolism Myocardium - ultrastructure Perfusion Reverse Transcriptase Polymerase Chain Reaction Time Factors Triglycerides - biosynthesis Triglycerides - metabolism
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