Huntington Disease Phenocopy Is a Familial Prion Disease

Huntington disease (HD) is a common autosomal dominant neurodegenerative disease with early adult–onset motor abnormalities and dementia. Many studies of HD show that huntingtin (CAG)n repeat–expansion length is a sensitive and specific marker for HD. However, there are a significant number of examp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of human genetics 2001-12, Vol.69 (6), p.1385-1388
Hauptverfasser:	Moore, Richard C., Xiang, Fengqing, Monaghan, Jeffrey, Han, Dong, Zhang, Zhiping, Edström, Lars, Anvret, Maria, Prusiner, Stanley B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Biological and medical sciences chromosome 20 Chromosome Mapping Chromosomes, Human, Pair 20 - genetics Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases DNA Mutational Analysis Genetic Testing - methods Humans Huntington Disease - genetics Huntington Disease - physiopathology Lod Score Medical sciences Medicin och hälsovetenskap Molecular Sequence Data Mutagenesis, Insertional - genetics Neurology Phenotype Prion Diseases - genetics Prion Diseases - physiopathology Prions - chemistry Prions - genetics PRNP gene Sequence Alignment
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!