Estrogen receptor beta in breast cancer

Estrogen is essential for normal growth and differentiation in the mammary gland. It also supports growth of approximately 50% of primary breast cancers. For this reason, removal of estrogen or blocking of its action with the anti-estrogen, tamoxifen, is the main treatment for estrogen receptor alph...

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Veröffentlicht in:	Endocrine-related cancer 2002-03, Vol.9 (1), p.1-13
Hauptverfasser:	Palmieri, C, Cheng, G J, Saji, S, Zelada-Hedman, M, W√§rri, A, Weihua, Z, Van Noorden, S, Wahlstrom, T, Coombes, R C, Warner, M, Gustafsson, J-A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Carcinoma, Ductal, Breast - metabolism Estrogen Receptor alpha Estrogen Receptor beta Female Humans Mice Neoplasms, Hormone-Dependent - drug therapy Neoplasms, Hormone-Dependent - metabolism Rats Receptors, Estrogen - analysis Receptors, Estrogen - biosynthesis Review Selective Estrogen Receptor Modulators - pharmacology Selective Estrogen Receptor Modulators - therapeutic use Support, Non-U.S. Gov't Tamoxifen - pharmacology Tamoxifen - therapeutic use
Online-Zugang:	Volltext
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