Up-regulation of the inflammatory cytokines IFN-γ and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP SWE transgenic mice

Alzheimer's disease (AD) is a progressive neurodegenerative disorder, of which the pathogenesis is thought to involve increased β-amyloid (Aβ) deposition and abnormal immunological responses. To elucidate the mechanisms involved in Aβ-mediated inflammation, we used immunocytochemistry and in si...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of neuroimmunology 2002, Vol.126 (1), p.50-57
Hauptverfasser:	Abbas, Nagat, Bednar, Ivan, Mix, Eilhard, Marie, Svedberg, Paterson, David, Ljungberg, Anna, Morris, Chris, Winblad, Bengt, Nordberg, Agneta, Zhu, Jie
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease APP APP SWE transgenic mouse Cytokines β-amyloid
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!