Interaction of Btk and Akt in B cell signaling

Reactive oxygen species (ROS) or reactive oxygen intermediates (ROIs) mediate complex signaling involving multiple pathways. In this report, we demonstrate for the first time that endogenous Bruton's tyrosine kinase (Btk) and Akt can interact with each other in DT40 chicken B cells and human Na...

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Veröffentlicht in:	Biochemical and biophysical research communications 2002-05, Vol.293 (5), p.1319-1326
Hauptverfasser:	Lindvall, Jessica, Islam, Tahmina C
Format:	Artikel
Sprache:	eng
Schlagworte:	Akt Animals B cells B-Lymphocytes - metabolism Btk Cell Line Chickens COS Cells Dose-Response Relationship, Drug Enzyme Inhibitors - pharmacology Hydrogen peroxide Hydrogen Peroxide - pharmacology Immunoblotting Medicin och hälsovetenskap Microscopy, Fluorescence Oxidative Stress Oxygen - metabolism Phosphatidylinositol 3-Kinases - metabolism Phosphorylation PI 3-K Precipitin Tests Protein Binding Protein-Serine-Threonine Kinases Protein-Tyrosine Kinases - metabolism Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins c-akt Signal Transduction Time Factors Transfection
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