Cross-clade HIV-1-specific neutralizing IgA in mucosal and systemic compartments of HIV-1-exposed, persistently seronegative subjects

There is an urgent need for a universally effective HIV-1 vaccine, but whether a vaccine will be able to protect against HIV-1 of different clades is a significant concern. IgA from HIV-1-exposed, persistently seronegative (HEPS) subjects has been shown to neutralize HIV-1 and to block epithelial HI...

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Veröffentlicht in:Journal of acquired immune deficiency syndromes (1999) 2002-08, Vol.30 (4), p.413-420
Hauptverfasser: DEVITO, Claudia, HINKULA, Jorma, PLUMMER, Francis, CLERICI, Mario, BROLIDEN, Kristina, KAUL, Rupert, KIMANI, Joshua, KIAMA, Peter, LOPALCO, Lucia, BARASS, Claudia, PICONI, Stefania, TRABATTONI, Daria, BWAYO, Job J
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Sprache:eng
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