Gain of 17q in malignant fibrous histiocytoma is associated with a longer disease-free survival and a low risk of developing distant metastasis

In this study, a panel of 39 primary malignant fibrous histiocytomas (MFH) of high malignancy grade were characterised for chromosomal alterations. The results were then evaluated in relation to the survival and the occurrence of recurrent disease during follow-up for an average period of 63 months....

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Veröffentlicht in:	British journal of cancer 2003-08, Vol.89 (4), p.720-726
Hauptverfasser:	Weng, W-H, Åhlén, J, Lui, W-O, Brosjö, O, Pang, S-T, von Rosen, A, Auer, G, Larsson, O, Larsson, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Biomarkers, Tumor Biomedical and Life Sciences Biomedicine Cancer Research Chromosome Aberrations Chromosomes, Human, Pair 17 - genetics Cyclin-dependent kinases Dermatology Disease-Free Survival DNA, Neoplasm - analysis Drug Resistance Epidemiology Female Genetics and Genomics Histiocytoma, Benign Fibrous - genetics Histiocytoma, Benign Fibrous - pathology Humans Kinases Male Medical prognosis Medical research Medical sciences Metaphase Metastasis Middle Aged Molecular Medicine Nucleic Acid Hybridization - genetics Oncology Prognosis Retrospective Studies Sarcoma Soft Tissue Neoplasms - genetics Soft Tissue Neoplasms - pathology Tumors Tumors of the skin and soft tissue. Premalignant lesions
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