Characterization of a novel B-CLL candidate gene – DLEU7 – located in the 13q14 tumor suppressor locus

Deletion of chromosome 13q14 is the most frequent genetic aberration in B-cell chronic lymphocytic leukemia (CLL), found in more than 50% of cases, indicating that this region contains a gene(s) involved in the development of CLL. However, the pathogenic gene in the critical 13q14 region has not yet...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	FEBS letters 2004-01, Vol.556 (1), p.75-80
Hauptverfasser:	Hammarsund, Marianne, Corcoran, Martin M., Wilson, William, Zhu, Chaoyong, Einhorn, Stefan, Sangfelt, Olle, Grandér, Dan
Format:	Artikel
Sprache:	eng
Schlagworte:	13q14 Amino Acid Sequence Animals Blotting, Northern Candidate gene Chromosomes, Human, Pair 13 - genetics Chronic lymphocytic leukemia Cloning, Molecular Deletion DLEU7 DNA Methylation DNA Mutational Analysis DNA Primers - genetics Gene Deletion Gene Expression Regulation, Leukemic Genes, Tumor Suppressor Humans Leukemia, Lymphocytic, Chronic, B-Cell - genetics Mice Molecular Sequence Data Neoplasm Proteins - genetics Promoter Regions, Genetic - genetics Proto-Oncogene Proteins Rats Sequence Alignment Sequence Homology, Amino Acid Tumor Suppressor Proteins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!