Keratin 8/18 breakdown and reorganization during apoptosis

Monoclonal antibodies that specifically recognize caspase cleaved K18 fragments or specific (phospho)epitopes on intact K8 and K18 were used for a detailed investigation of the temporal and causal relationship of proteolysis and phosphorylation in the collapse of the keratin cytoskeleton during apop...

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Veröffentlicht in:	Experimental cell research 2004-07, Vol.297 (1), p.11-26
Hauptverfasser:	Schutte, Bert, Henfling, Mieke, Kölgen, Wendy, Bouman, Maartje, Meex, Stephan, Leers, Mathie P.G, Nap, Marius, Björklund, Viveka, Björklund, Peter, Björklund, Bertil, Lane, E.Birgitte, Omary, M.Bishr, Jörnvall, Hans, Ramaekers, Frans C.S
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - physiology Caspase Caspase 3 Caspase 7 Caspase 9 Caspases - metabolism Catalytic Domain - physiology Cell Line, Tumor Cell Membrane - metabolism Cytoskeleton Cytoskeleton - metabolism Humans Keratin Keratin-18 Keratin-8 Keratins - metabolism M30-CytoDeath Phosphorylation Protein Structure, Tertiary - physiology
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