Endometrial TIMP-4 mRNA is high at midcycle and in hyperplasia, but down-regulated in malignant tumours. Coordinated expression with MMP-26

We have previously reported that endometrial expression of matrix metalloproteinase (MMP)-26 mRNA comes to a maximum in the early secretory phase. Since tissue inhibitor of metalloproteinase (TIMP)-4 is a potent inhibitor of MMP-26, the objective of this study was to identify the pattern of TIMP-4 m...

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Veröffentlicht in:	Molecular human reproduction 2004-09, Vol.10 (9), p.641-650
Hauptverfasser:	Pilka, R., Domanski, H., Hansson, S., Eriksson, P., Casslén, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Base Sequence Biological and medical sciences Clinical Medicine Embryology: invertebrates and vertebrates. Teratology Endometrial Hyperplasia - metabolism Endometrial Neoplasms - metabolism Endometrial Neoplasms - pathology Endometrium - cytology Endometrium - pathology Endometrium - physiology estrogen receptor Female Fundamental and applied biological sciences. Psychology Gene Expression Regulation human Humans implantation In Situ Hybridization Klinisk medicin Matrix Metalloproteinases - metabolism Matrix Metalloproteinases, Secreted Medical and Health Sciences Medicin och hälsovetenskap Menstrual Cycle - physiology Middle Aged Molecular Sequence Data Obstetrics, Gynecology and Reproductive Medicine pre-malignant Promoter Regions, Genetic protease inhibitor Reproduktionsmedicin och gynekologi RNA, Messenger - metabolism Tissue Inhibitor of Metalloproteinase-4 Tissue Inhibitor of Metalloproteinases - genetics Tissue Inhibitor of Metalloproteinases - metabolism
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