Effect of combined T- and B-cell depletion of allogeneic HLA-mismatched bone marrow graft on the magnitude and kinetics of Epstein-Barr virus load in the peripheral blood of bone marrow transplant recipients

: Recipients of T‐cell‐depleted bone marrow (BM) transplants (BMT) frequently develop Epstein–Barr virus (EBV)‐associated post‐transplant lymphoproliferative disease (PTLD) preceded by a rapid and prominent increase of EBV load in the peripheral blood. The level of this increase positively correlat...

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Veröffentlicht in:	Clinical transplantation 2004-10, Vol.18 (5), p.518-524
Hauptverfasser:	Liu, Daorong, Tammik, Charlotte, Zou, Jie-Zhi, Ernberg, Ingemar, Masucci, Maria G., Ringden, Olle, Levitsky, Victor
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adolescent Adult B-cell B-Lymphocytes - pathology Biological and medical sciences Bone Marrow Transplantation - pathology Cardiology. Vascular system Child, Preschool Epstein-Barr virus Epstein-Barr Virus Infections - prevention & control Female Follow-Up Studies General aspects Hematologic and hematopoietic diseases Herpesvirus 4, Human - isolation & purification Herpesvirus 4, Human - physiology Histocompatibility - immunology HLA Antigens - immunology Humans Leukemia, Myeloid - therapy Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Leukocyte Reduction Procedures - methods lymphoma Male Medical sciences Medicin och hälsovetenskap Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - therapy Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy T-Lymphocytes - pathology Transplantation Conditioning Transplantation, Homologous Viral Load Viremia - virology
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