Differential distribution of estrogen receptor (ER)-α and ER-β in the midbrain raphe nuclei and periaqueductal gray in male mouse: Predominant role of ER-β in midbrain serotonergic systems

We examined the distribution of estrogen receptor (ER)-α and ER-β immunoreactive (ir) cells in the dorsal (DRN) and median/paramedian (MPRN) raphe nuclei in male mice. ER-α ir neurons were scattered across the three subdivisions (ventral, dorsal, and lateral) of the DRN and the MPRN. Robust ER-β ir...

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Veröffentlicht in:	Neuroscience 2005, Vol.130 (2), p.445-456
Hauptverfasser:	Nomura, M., Akama, K.T., Alves, S.E., Korach, K.S., Gustafsson, J.-Å., Pfaff, D.W., Ogawa, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	aggression Animals Biological and medical sciences Estrogen Receptor alpha - genetics Estrogen Receptor alpha - metabolism Estrogen Receptor beta - genetics Estrogen Receptor beta - metabolism Fundamental and applied biological sciences. Psychology Gene Expression Regulation - physiology immunocytochemistry Immunohistochemistry knockout mouse Male Mice Mice, Knockout Neural Pathways - anatomy & histology Neural Pathways - metabolism Neurons - metabolism Periaqueductal Gray - anatomy & histology Periaqueductal Gray - metabolism Raphe Nuclei - anatomy & histology Raphe Nuclei - metabolism RNA, Messenger - metabolism serotonin Serotonin - metabolism Sex Factors sexual behavior tryptophan hydroxylase Tryptophan Hydroxylase - genetics Tryptophan Hydroxylase - metabolism Vertebrates: nervous system and sense organs
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