Apoptosis and angiogenesis are induced in the unstable coronary atherosclerotic plaque

OBJECTIVEApoptosis and angiogenesis may be involved in the pathogenesis of atherosclerosis and plaque destabilization. In this study, we investigated if apoptosis and angiogenesis were induced in the unstable human coronary atherosclerotic plaque compared to stable atherosclerotic plaque. METHODSAth...

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Veröffentlicht in:	Coronary artery disease 2005-05, Vol.16 (3), p.191-197
Hauptverfasser:	Chen, Fei, Eriksson, Per, Kimura, Tamizo, Herzfeld, Istvan, Valen, Guro
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Angina, Unstable - metabolism Angina, Unstable - pathology Angioplasty, Balloon, Coronary Angiopoietins - analysis Apoptosis bcl-2-Associated X Protein Caspase 3 Caspases - analysis Coronary Artery Disease - metabolism Coronary Artery Disease - pathology Female Humans Hypoxia-Inducible Factor 1, alpha Subunit Immunohistochemistry In Situ Nick-End Labeling Male Medicin och hälsovetenskap Middle Aged Neovascularization, Pathologic Platelet Endothelial Cell Adhesion Molecule-1 - analysis Proto-Oncogene Proteins c-bcl-2 - analysis Transcription Factors - analysis Vascular Endothelial Growth Factor A - analysis
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