SOD-1 inhibits FAS expression in cortex of APP transgenic mice

Peptides derived from proteolytic processing of the amyloid precursor protein (APP) are important for the pathogenesis of Alzheimer's disease (AD). In the present study, we found that transgenic mice overexpressing wild-type human APP gene (hAPP/+) displayed a much higher expression of FAS, one...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Apoptosis (London) 2005-05, Vol.10 (3), p.499-502
Hauptverfasser:	Chen, Z, Duan, R-S, Lepécheur, M, Paly, E, London, J, Zhu, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - physiopathology Alzheimer's disease Amyloid beta-Protein Precursor - biosynthesis Animals Cerebral Cortex - drug effects Cerebral Cortex - metabolism fas Receptor - biosynthesis Glial Fibrillary Acidic Protein - biosynthesis Humans Male Medicin och hälsovetenskap Mice Mice, Transgenic Peptides Rodents Superoxide Dismutase - metabolism Superoxide Dismutase-1
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!