Variants of the SFTPA1 and SFTPA2 genes and susceptibility to tuberculosis in Ethiopia

Lungs are the central organ affected and targeted by Mycobacterium tuberculosis and immune processes in the lung are of critical importance in the pathogenesis of tuberculosis. A major lung defense against invading pathogens is provided by surfactant protein A, a multi-chain protein encoded by the S...

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Veröffentlicht in:	Human genetics 2006-02, Vol.118 (6), p.752-759
Hauptverfasser:	MALIK, S, GREENWOOD, C. M. T, EGUALE, T, KIFLE, A, BEYENE, J, HABTE, A, TADESSE, A, GEBREXABHER, H, BRITTON, S, SCHURR, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Bacterial diseases Biological and medical sciences Child Classical genetics, quantitative genetics, hybrids Disease Disease Progression Ethiopia Family Female Fundamental and applied biological sciences. Psychology Gene Frequency Genes Genetic Predisposition to Disease Genetic Testing Genetics of eukaryotes. Biological and molecular evolution Hospitals Human Human bacterial diseases Humans Infections Infectious diseases Investigations Lungs Male Medical sciences Mycobacterium tuberculosis Pathogens Polymorphism, Genetic Proteins Pulmonary Surfactant-Associated Protein A - genetics Respiratory distress syndrome Surfactants Tuberculosis Tuberculosis - genetics Tuberculosis and atypical mycobacterial infections
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