Changes of gastric mucosal architecture during long‐term omeprazole therapy: results of a randomized clinical trial

Summary Background The impact of long‐term acid suppression on the gastric mucosa remains controversial. Aim To report further observations on an established cohort of patients with gastro‐oesophageal reflux disease, after 7 years of follow‐up. Methods Of the original cohort randomized to either...

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Veröffentlicht in:	Alimentary pharmacology & therapeutics 2006-03, Vol.23 (5), p.639-647
Hauptverfasser:	LUNDELL, L., HAVU, N., MIETTINEN, P., MYRVOLD, H. E., WALLIN, L., JULKUNEN, R., LEVANDER, K., HATLEBAKK, J. G., LIEDMAN, B., LAMM, M., MALM, A., WALAN, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anti-Ulcer Agents - therapeutic use Atrophy Biological and medical sciences Digestive system Enteroendocrine Cells - pathology Female Gastric Acid - metabolism Gastric Mucosa - drug effects Gastric Mucosa - pathology Gastroenterology. Liver. Pancreas. Abdomen Gastroesophageal Reflux - complications Gastroesophageal Reflux - drug therapy Gastroesophageal Reflux - surgery Helicobacter Infections - complications Helicobacter Infections - drug therapy Helicobacter pylori Humans Male Medical sciences Middle Aged Omeprazole - therapeutic use Pharmacology. Drug treatments Severity of Illness Index
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