Long-term outcome of abdominal sacrocolpopexy using xenograft compared with synthetic mesh
To assess the clinical outcome after abdominal sacrocolpopexy using a porcine dermal graft compared with a synthetic mesh. Patients with vaginal vault prolapse Stage II or worse (Baden-Walker staging), underwent sacrocolpopexy using a synthetic mesh (n = 25) or porcine collagen graft (n = 27). The s...
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| Veröffentlicht in: | Urology (Ridgewood, N.J.) N.J.), 2006-04, Vol.67 (4), p.719-724 |
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| creator | Altman, Daniel Anzen, Bo Brismar, Sophia Lopez, Annika Zetterström, Jan |
| description | To assess the clinical outcome after abdominal sacrocolpopexy using a porcine dermal graft compared with a synthetic mesh.
Patients with vaginal vault prolapse Stage II or worse (Baden-Walker staging), underwent sacrocolpopexy using a synthetic mesh (n = 25) or porcine collagen graft (n = 27). The subjective outcome was measured using validated questionnaires.
The mean clinical follow-up from surgery was 7.1 months for the xenograft compared with 7.4 months for the synthetic cohort. At clinical follow-up, vaginal vault prolapse Stage II was present in 8 (29%) of 27 patients in the xenograft cohort and 6 (24%) of 25 patients in the synthetic mesh cohort (no significant difference). The mean follow-up from surgery to survey was 2.5 years in the xenograft cohort and 4.3 years in the synthetic cohort. None of the patients in either cohort had undergone a secondary sacrocolpopexy. No significant differences were found between the cohorts regarding surgical morbidity other than more patients experiencing fever for 1 to 3 days in the xenograft cohort (
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| doi_str_mv | 10.1016/j.urology.2005.10.034 |
| format | Article |
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Patients with vaginal vault prolapse Stage II or worse (Baden-Walker staging), underwent sacrocolpopexy using a synthetic mesh (n = 25) or porcine collagen graft (n = 27). The subjective outcome was measured using validated questionnaires.
The mean clinical follow-up from surgery was 7.1 months for the xenograft compared with 7.4 months for the synthetic cohort. At clinical follow-up, vaginal vault prolapse Stage II was present in 8 (29%) of 27 patients in the xenograft cohort and 6 (24%) of 25 patients in the synthetic mesh cohort (no significant difference). The mean follow-up from surgery to survey was 2.5 years in the xenograft cohort and 4.3 years in the synthetic cohort. None of the patients in either cohort had undergone a secondary sacrocolpopexy. No significant differences were found between the cohorts regarding surgical morbidity other than more patients experiencing fever for 1 to 3 days in the xenograft cohort (
P <0.001). No significant differences were found in lower urinary tract symptoms, anorectal symptoms, or quality-of-life variables between the two cohorts.
Abdominal sacrocolpopexy using a porcine dermal graft was comparable to synthetic mesh in terms of subjective and anatomic outcomes at mid to long-term follow-up.</description><identifier>ISSN: 0090-4295</identifier><identifier>EISSN: 1527-9995</identifier><identifier>DOI: 10.1016/j.urology.2005.10.034</identifier><identifier>PMID: 16566983</identifier><identifier>CODEN: URGYAZ</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aged ; Aged, 80 and over ; Animals ; Biological and medical sciences ; Cervix Uteri ; Cohort Studies ; Female ; Humans ; Medical sciences ; Middle Aged ; Nephrology. Urinary tract diseases ; Retrospective Studies ; Sacrum ; Skin Transplantation ; Surgical Mesh ; Swine ; Time Factors ; Transplantation, Heterologous ; Treatment Outcome ; Urologic Surgical Procedures - methods ; Uterine Prolapse - surgery</subject><ispartof>Urology (Ridgewood, N.J.), 2006-04, Vol.67 (4), p.719-724</ispartof><rights>2006 Elsevier Inc.</rights><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c431t-3dcc9a428cb63e6d1f2bdcbe44eaa108c3aff42616385b7c81e1c9b87f6cc0a73</citedby><cites>FETCH-LOGICAL-c431t-3dcc9a428cb63e6d1f2bdcbe44eaa108c3aff42616385b7c81e1c9b87f6cc0a73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0090429505015396$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,309,310,314,776,780,785,786,881,3537,23909,23910,25118,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17712481$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16566983$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:1959940$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Altman, Daniel</creatorcontrib><creatorcontrib>Anzen, Bo</creatorcontrib><creatorcontrib>Brismar, Sophia</creatorcontrib><creatorcontrib>Lopez, Annika</creatorcontrib><creatorcontrib>Zetterström, Jan</creatorcontrib><title>Long-term outcome of abdominal sacrocolpopexy using xenograft compared with synthetic mesh</title><title>Urology (Ridgewood, N.J.)</title><addtitle>Urology</addtitle><description>To assess the clinical outcome after abdominal sacrocolpopexy using a porcine dermal graft compared with a synthetic mesh.
Patients with vaginal vault prolapse Stage II or worse (Baden-Walker staging), underwent sacrocolpopexy using a synthetic mesh (n = 25) or porcine collagen graft (n = 27). The subjective outcome was measured using validated questionnaires.
The mean clinical follow-up from surgery was 7.1 months for the xenograft compared with 7.4 months for the synthetic cohort. At clinical follow-up, vaginal vault prolapse Stage II was present in 8 (29%) of 27 patients in the xenograft cohort and 6 (24%) of 25 patients in the synthetic mesh cohort (no significant difference). The mean follow-up from surgery to survey was 2.5 years in the xenograft cohort and 4.3 years in the synthetic cohort. None of the patients in either cohort had undergone a secondary sacrocolpopexy. No significant differences were found between the cohorts regarding surgical morbidity other than more patients experiencing fever for 1 to 3 days in the xenograft cohort (
P <0.001). No significant differences were found in lower urinary tract symptoms, anorectal symptoms, or quality-of-life variables between the two cohorts.
Abdominal sacrocolpopexy using a porcine dermal graft was comparable to synthetic mesh in terms of subjective and anatomic outcomes at mid to long-term follow-up.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Cervix Uteri</subject><subject>Cohort Studies</subject><subject>Female</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Retrospective Studies</subject><subject>Sacrum</subject><subject>Skin Transplantation</subject><subject>Surgical Mesh</subject><subject>Swine</subject><subject>Time Factors</subject><subject>Transplantation, Heterologous</subject><subject>Treatment Outcome</subject><subject>Urologic Surgical Procedures - methods</subject><subject>Uterine Prolapse - surgery</subject><issn>0090-4295</issn><issn>1527-9995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkcGP1CAYxYnRuLOrf4KGi946QinQnozZqGsyiRe9eCH069cZxrZUoLs7_71MpnGPniAvv_cg7xHyhrMtZ1x9OG6X4Ae_P21LxmTWtkxUz8iGy1IXTdPI52TDWMOKqmzkFbmO8cgYU0rpl-SKK6lUU4sN-bXz075IGEbqlwR-ROp7atvOj26yA40Wggc_zH7GxxNdopv29BEnvw-2TzQbZhuwow8uHWg8TemAyQEdMR5ekRe9HSK-Xs8b8vPL5x-3d8Xu-9dvt592BVSCp0J0AI2tyhpaJVB1vC_bDlqsKrSWsxqE7fuqVFyJWrYaao4cmrbWvQJgVosbUlxy4wPOS2vm4EYbTsZbZ1bpd76hkVqVWmb-_YWfg_-zYExmdBFwGOyEfolG6VoLyc_B8gLmCmIM2P-L5sycRzBHs45gziOc5TxC9r1dH1jaEbsn19p6Bt6tgI1ghz7YCVx84rTmZVXzzH28cJjru3cYTASHE2DnAkIynXf_-cpfLsGruA</recordid><startdate>20060401</startdate><enddate>20060401</enddate><creator>Altman, Daniel</creator><creator>Anzen, Bo</creator><creator>Brismar, Sophia</creator><creator>Lopez, Annika</creator><creator>Zetterström, Jan</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>ADTPV</scope><scope>BNKNJ</scope></search><sort><creationdate>20060401</creationdate><title>Long-term outcome of abdominal sacrocolpopexy using xenograft compared with synthetic mesh</title><author>Altman, Daniel ; Anzen, Bo ; Brismar, Sophia ; Lopez, Annika ; Zetterström, Jan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c431t-3dcc9a428cb63e6d1f2bdcbe44eaa108c3aff42616385b7c81e1c9b87f6cc0a73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Cervix Uteri</topic><topic>Cohort Studies</topic><topic>Female</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Retrospective Studies</topic><topic>Sacrum</topic><topic>Skin Transplantation</topic><topic>Surgical Mesh</topic><topic>Swine</topic><topic>Time Factors</topic><topic>Transplantation, Heterologous</topic><topic>Treatment Outcome</topic><topic>Urologic Surgical Procedures - methods</topic><topic>Uterine Prolapse - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Altman, Daniel</creatorcontrib><creatorcontrib>Anzen, Bo</creatorcontrib><creatorcontrib>Brismar, Sophia</creatorcontrib><creatorcontrib>Lopez, Annika</creatorcontrib><creatorcontrib>Zetterström, Jan</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>SwePub</collection><collection>SwePub Conference</collection><jtitle>Urology (Ridgewood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Altman, Daniel</au><au>Anzen, Bo</au><au>Brismar, Sophia</au><au>Lopez, Annika</au><au>Zetterström, Jan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-term outcome of abdominal sacrocolpopexy using xenograft compared with synthetic mesh</atitle><jtitle>Urology (Ridgewood, N.J.)</jtitle><addtitle>Urology</addtitle><date>2006-04-01</date><risdate>2006</risdate><volume>67</volume><issue>4</issue><spage>719</spage><epage>724</epage><pages>719-724</pages><issn>0090-4295</issn><eissn>1527-9995</eissn><coden>URGYAZ</coden><abstract>To assess the clinical outcome after abdominal sacrocolpopexy using a porcine dermal graft compared with a synthetic mesh.
Patients with vaginal vault prolapse Stage II or worse (Baden-Walker staging), underwent sacrocolpopexy using a synthetic mesh (n = 25) or porcine collagen graft (n = 27). The subjective outcome was measured using validated questionnaires.
The mean clinical follow-up from surgery was 7.1 months for the xenograft compared with 7.4 months for the synthetic cohort. At clinical follow-up, vaginal vault prolapse Stage II was present in 8 (29%) of 27 patients in the xenograft cohort and 6 (24%) of 25 patients in the synthetic mesh cohort (no significant difference). The mean follow-up from surgery to survey was 2.5 years in the xenograft cohort and 4.3 years in the synthetic cohort. None of the patients in either cohort had undergone a secondary sacrocolpopexy. No significant differences were found between the cohorts regarding surgical morbidity other than more patients experiencing fever for 1 to 3 days in the xenograft cohort (
P <0.001). No significant differences were found in lower urinary tract symptoms, anorectal symptoms, or quality-of-life variables between the two cohorts.
Abdominal sacrocolpopexy using a porcine dermal graft was comparable to synthetic mesh in terms of subjective and anatomic outcomes at mid to long-term follow-up.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>16566983</pmid><doi>10.1016/j.urology.2005.10.034</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Aged Aged, 80 and over Animals Biological and medical sciences Cervix Uteri Cohort Studies Female Humans Medical sciences Middle Aged Nephrology. Urinary tract diseases Retrospective Studies Sacrum Skin Transplantation Surgical Mesh Swine Time Factors Transplantation, Heterologous Treatment Outcome Urologic Surgical Procedures - methods Uterine Prolapse - surgery |
| title | Long-term outcome of abdominal sacrocolpopexy using xenograft compared with synthetic mesh |
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