Contribution of adenosine receptors in the control of arteriolar tone and adenosine–angiotensin II interaction

Adenosine (Ado) mediates vasoconstriction via A1-Ado receptors and vasodilation via A2-Ado receptors in the kidney. It interacts with angiotensin II (Ang II), which is important for renal hemodynamics and tubuloglomerular feedback (TGF). The aim was to investigate the function of Ado receptors in th...

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Veröffentlicht in:	Kidney international 2006-08, Vol.70 (4), p.690-698
Hauptverfasser:	Lai, E.Y., Patzak, A., Steege, A., Mrowka, R., Brown, R., Spielmann, N., Persson, P.B., Fredholm, B.B., Persson, A.E.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	adenosine Adenosine - analogs & derivatives Adenosine - pharmacology Adenosine - physiology Adenosine A1 Receptor Agonists Adenosine A1 Receptor Antagonists Adenosine A2 Receptor Agonists Adenosine A2 Receptor Antagonists adenosine type 1 receptor knockout mouse adenosine-angiotensin II interaction afferent arteriole Angiotensin II - physiology Animals Arterioles - physiology Biological and medical sciences Feedback - drug effects Feedback - physiology Female Kidney Glomerulus - blood supply Kidney Glomerulus - physiology Kidney Tubules - blood supply Kidney Tubules - physiology Male Medical sciences MEDICIN MEDICINE Mice Mice, Inbred C57BL Mice, Knockout mouse Nephrology. Urinary tract diseases Phenethylamines - pharmacology Purines - pharmacology Receptor, Adenosine A1 - drug effects Receptor, Adenosine A1 - physiology Receptors, Adenosine A2 - drug effects Receptors, Adenosine A2 - physiology Theophylline - analogs & derivatives Theophylline - pharmacology Triazines - pharmacology Triazoles - pharmacology Vasoconstriction - drug effects Vasoconstriction - physiology Vasodilation - drug effects Vasodilation - physiology
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