Polymorphisms in the DNA repair genes XRCC1, APEX1, XRCC3 and NBS1, and the risk for lung cancer in never- and ever-smokers

This case–control study examines the association between lung cancer and genetic polymorphisms in two base excision repair (BER) genes, XRCC1 and APEX1 and two genes involved in homologous recombination repair (HR), XRCC3 and NBS1. Never-smoking lung cancer patients were recruited, and also the next...

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Veröffentlicht in:	Lung cancer (Amsterdam, Netherlands) Netherlands), 2006-12, Vol.54 (3), p.285-292
Hauptverfasser:	Ryk, Charlotta, Kumar, Rajiv, Thirumaran, Ranjit K., Hou, Sai-Mei
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Base excision repair Biological and medical sciences Cell Cycle Proteins - genetics DNA Repair - genetics DNA-(Apurinic or Apyrimidinic Site) Lyase - genetics DNA-Binding Proteins - genetics Female Gender Homologous recombination repair Humans Lung cancer Lung Neoplasms - genetics Male Medical sciences Middle Aged Non-smokers Nuclear Proteins - genetics Pneumology Polymorphism, Genetic Recombination, Genetic - genetics Repair polymorphism Smoking Tumors Tumors of the respiratory system and mediastinum X-ray Repair Cross Complementing Protein 1
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