Head-to-head comparison on the immunogenicity of two HIV/AIDS vaccine candidates based on the attenuated poxvirus strains MVA and NYVAC co-expressing in a single locus the HIV-1 BX08 gp120 and HIV-1 IIIB Gag-Pol-Nef proteins of clade B

In this investigation we have generated and defined the immunogenicity of two novel HIV/AIDS vaccine candidates based on the highly attenuated vaccinia virus strains, MVA and NYVAC, efficiently expressing in the same locus (TK) and under the same viral promoter the codon optimized HIV-1 genes encodi...

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Veröffentlicht in:	Vaccine 2007, Vol.25 (15), p.2863-2885
Hauptverfasser:	Gómez, Carmen Elena, Nájera, Jose Luis, Jiménez, Eva Pérez, Jiménez, Victoria, Wagner, Ralf, Graf, Marcus, Frachette, Marie-Joelle, Liljeström, Peter, Pantaleo, Giuseppe, Esteban, Mariano
Format:	Artikel
Sprache:	eng
Schlagworte:	Clade B vaccine HIV/AIDS Immune response Mouse models MVA NYVAC Poxvirus vectors
Online-Zugang:	Volltext
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